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TargetUDP-glucuronosyltransferase 1A7
LigandBDBM13066
Substrate/Competitorn/a
Meas. Tech.ChEMBL_774123 (CHEMBL1908128)
Ki 19000±n/a nM
Citation Kiang, TK; Ensom, MH; Chang, TK UDP-glucuronosyltransferases and clinical drug-drug interactions. Pharmacol Ther106:97-132 (2005) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
UDP-glucuronosyltransferase 1A7
Name:UDP-glucuronosyltransferase 1A7
Synonyms:GNT1 | UD17_HUMAN | UDP-glucuronosyltransferase 1-7 | UDP-glucuronosyltransferase 1-G | UDP-glucuronosyltransferase 1A7 | UDPGT 1-7 | UGT-1G | UGT1 | UGT1*7 | UGT1-07 | UGT1.7 | UGT1A7 | UGT1G
Type:PROTEIN
Mol. Mass.:59829.76
Organism:Homo sapiens (Human)
Description:ChEMBL_1489264
Residue:530
Sequence:
MARAGWTGLLPLYVCLLLTCGFAKAGKLLVVPMDGSHWFTMQSVVEKLILRGHEVVVVMP
EVSWQLGRSLNCTVKTYSTSYTLEDQDREFMVFADARWTAPLRSAFSLLTSSSNGIFDLF
FSNCRSLFNDRKLVEYLKESCFDAVFLDPFDACGLIVAKYFSLPSVVFARGIFCHYLEEG
AQCPAPLSYVPRLLLGFSDAMTFKERVWNHIMHLEEHLFCPYFFKNVLEIASEILQTPVT
AYDLYSHTSIWLLRTDFVLEYPKPVMPNMIFIGGINCHQGKPVPMEFEAYINASGEHGIV
VFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSNLANNTILVKWLPQNDLLGH
PMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMTSEDL
ENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAAHDLTW
YQYHSLDVIGFLLAVVLTVAFITFKCCAYGYRKCLGKKGRVKKAHKSKTH
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM13066
n/a
NameBDBM13066
Synonyms:2-{2-[(2,6-dichlorophenyl)amino]phenyl}acetic acid | CHEMBL139 | Diclofenac | US11337935, Compound Diclofenac | US11478464, Compound Diclofenac | US11786535, Compound Diclofenac | {2-[(2,6-dichlorophenyl)amino]phenyl}acetic acid
TypeSmall organic molecule
Emp. Form.C14H11Cl2NO2
Mol. Mass.296.149
SMILESOC(=O)Cc1ccccc1Nc1c(Cl)cccc1Cl
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: