Reaction Details |
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Target | Interleukin-1 beta |
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Ligand | BDBM50355791 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_776544 (CHEMBL1913641) |
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IC50 | 34300±n/a nM |
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Citation | Stierle, DB; Stierle, AA; Patacini, B; McIntyre, K; Girtsman, T; Bolstad, E Berkeleyones and related meroterpenes from a deep water acid mine waste fungus that inhibit the production of interleukin 1-ß from induced inflammasomes. J Nat Prod74:2273-7 (2011) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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Interleukin-1 beta |
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Name: | Interleukin-1 beta |
Synonyms: | IL1B | IL1B_HUMAN | IL1F2 | Interleukin 1-beta | Interleukin-1 beta | hIL-1beta |
Type: | Cytokine |
Mol. Mass.: | 30734.47 |
Organism: | Homo sapiens (Human) |
Description: | P01584 |
Residue: | 269 |
Sequence: | MAEVPELASEMMAYYSGNEDDLFFEADGPKQMKCSFQDLDLCPLDGGIQLRISDHHYSKG
FRQAASVVVAMDKLRKMLVPCPQTFQENDLSTFFPFIFEEEPIFFDTWDNEAYVHDAPVR
SLNCTLRDSQQKSLVMSGPYELKALHLQGQDMEQQVVFSMSFVQGEESNDKIPVALGLKE
KNLYLSCVLKDDKPTLQLESVDPKNYPKKKMEKRFVFNKIEINNKLEFESAQFPNWYIST
SQAENMPVFLGGTKGGQDITDFTMQFVSS
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BDBM50355791 |
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n/a |
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Name | BDBM50355791 |
Synonyms: | CHEMBL1911629 |
Type | Small organic molecule |
Emp. Form. | C26H36O7 |
Mol. Mass. | 460.5598 |
SMILES | COC(=O)[C@@]12C(=C)[C@@](C)(C[C@H]3[C@]4(C)CCC(=O)OC(C)(C)[C@@H]4CC[C@]13C)C(=O)[C@](C)(O)C2=O |r,THB:6:5:10.24.9:26.31.28| |
Structure |
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