| Reaction Details |
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 | Report a problem with these data |
| Target | Toll-like receptor 4 |
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| Ligand | BDBM50355887 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_775690 (CHEMBL1913432) |
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| IC50 | 28800±n/a nM |
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| Citation |  Ainge, GD; Martin, WJ; Compton, BJ; Hayman, CM; Larsen, DS; Yoon, SI; Wilson, IA; Harper, JL; Painter, GF Synthesis and Toll-like receptor 4 (TLR4) activity of phosphatidylinositol dimannoside analogues. J Med Chem54:7268-79 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Toll-like receptor 4 |
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| Name: | Toll-like receptor 4 |
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| Synonyms: | CD_antigen=CD284 | Lps | TLR4_MOUSE | Tlr4 | Toll-like receptor 4 | Toll-like receptor 4/Ly96 | Toll-like receptor 4/MD-2/CD14 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 95518.84 |
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| Organism: | Mus musculus |
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| Description: | ChEMBL_1496719 |
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| Residue: | 835 |
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| Sequence: | MMPPWLLARTLIMALFFSCLTPGSLNPCIEVVPNITYQCMDQKLSKVPDDIPSSTKNIDL
SFNPLKILKSYSFSNFSELQWLDLSRCEIETIEDKAWHGLHHLSNLILTGNPIQSFSPGS
FSGLTSLENLVAVETKLASLESFPIGQLITLKKLNVAHNFIHSCKLPAYFSNLTNLVHVD
LSYNYIQTITVNDLQFLRENPQVNLSLDMSLNPIDFIQDQAFQGIKLHELTLRGNFNSSN
IMKTCLQNLAGLHVHRLILGEFKDERNLEIFEPSIMEGLCDVTIDEFRLTYTNDFSDDIV
KFHCLANVSAMSLAGVSIKYLEDVPKHFKWQSLSIIRCQLKQFPTLDLPFLKSLTLTMNK
GSISFKKVALPSLSYLDLSRNALSFSGCCSYSDLGTNSLRHLDLSFNGAIIMSANFMGLE
ELQHLDFQHSTLKRVTEFSAFLSLEKLLYLDISYTNTKIDFDGIFLGLTSLNTLKMAGNS
FKDNTLSNVFANTTNLTFLDLSKCQLEQISWGVFDTLHRLQLLNMSHNNLLFLDSSHYNQ
LYSLSTLDCSFNRIETSKGILQHFPKSLAFFNLTNNSVACICEHQKFLQWVKEQKQFLVN
VEQMTCATPVEMNTSLVLDFNNSTCYMYKTIISVSVVSVIVVSTVAFLIYHFYFHLILIA
GCKKYSRGESIYDAFVIYSSQNEDWVRNELVKNLEEGVPRFHLCLHYRDFIPGVAIAANI
IQEGFHKSRKVIVVVSRHFIQSRWCIFEYEIAQTWQFLSSRSGIIFIVLEKVEKSLLRQQ
VELYRLLSRNTYLEWEDNPLGRHIFWRRLKNALLDGKASNPEQTAEEEQETATWT
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| BDBM50355887 |
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| n/a |
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| Name | BDBM50355887 |
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| Synonyms: | CHEMBL1910029 |
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| Type | Small organic molecule |
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| Emp. Form. | C53H101O22P |
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| Mol. Mass. | 1121.3296 |
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| SMILES | CCCCCCCCCCCCCCCCOC[C@H](COP(O)(=O)O[C@H]1[C@H](O[C@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]2O)[C@@H](O)[C@H](O)[C@@H](O)[C@H]1O[C@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]1O)OC(=O)CCCCCCCCCCCCCCC |r| |
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| Structure | 
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