| Reaction Details |
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 | Report a problem with these data |
| Target | Cannabinoid receptor 1 |
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| Ligand | BDBM50356013 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_775080 (CHEMBL1912275) |
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| Kd | 29.1±n/a nM |
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| Citation |  Yang, Y; Miller, KJ; Zhu, Y; Hong, Y; Tian, Y; Murugesan, N; Gu, Z; O'Tanyi, E; Keim, WJ; Rohrbach, KW; Johnghar, S; Behnia, K; Pelleymounter, MA; Carlson, KE; Ewing, WR Characterization of a novel and selective CB1 antagonist as a radioligand for receptor occupancy studies. Bioorg Med Chem Lett21:6856-60 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cannabinoid receptor 1 |
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| Name: | Cannabinoid receptor 1 |
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| Synonyms: | Brain-type cannabinoid receptor | CANNABINOID CB1 | CB-R | CB1 | CNR1_RAT | Cannabinoid CB1 receptor | Cannabinoid receptor | Cannabinoid receptor 1 (CB1) | Cnr1 | Skr6 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 52856.55 |
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| Organism: | Rattus norvegicus (rat) |
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| Description: | P20272 |
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| Residue: | 473 |
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| Sequence: | MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQE
KMTAGDNSPLVPAGDTTNITEFYNKSLSSFKENEENIQCGENFMDMECFMILNPSQQLAI
AVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFVDFHV
FHRKDSPNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCL
MWTIAIVIAVLPLLGWNCKKLQSVCSDIFPLIDETYLMFWIGVTSVLLLFIVYAYMYILW
KAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPL
LAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTA
QPLDNSMGDSDCLHKHANNTASMHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
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| BDBM50356013 |
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| n/a |
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| Name | BDBM50356013 |
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| Synonyms: | CHEMBL1911374 | CHEMBL1911375 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H14ClF3N6O |
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| Mol. Mass. | 482.845 |
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| SMILES | FC(F)(F)c1ccc(Cn2nc3c(-c4ccncc4)c(cnn3c2=O)-c2ccc(Cl)cc2)cn1 |
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| Structure | 
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