| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Sigma non-opioid intracellular receptor 1 |
|---|
| Ligand | BDBM50334158 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_787915 (CHEMBL1918797) |
|---|
| Ki | 0.59±n/a nM |
|---|
| Citation |  Moussa, IA; Banister, SD; Giboureau, N; Meikle, SR; Kassiou, M Synthesis and in vivo evaluation of [18F]N-(2-benzofuranylmethyl)-N'-[4-(2-fluoroethoxy)benzyl]piperazine, a novels1 receptor PET imaging agent. Bioorg Med Chem Lett21:6820-3 (2011) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Sigma non-opioid intracellular receptor 1 |
|---|
| Name: | Sigma non-opioid intracellular receptor 1 |
|---|
| Synonyms: | Aging-associated gene 8 protein | OPRS1 | SGMR1_HUMAN | SIG-1R | SIGMAR1 | SR-BP | SR31747-binding protein | SRBP | Sigma 1-type opioid receptor | Sigma opioid receptor | Sigma1R | hSigmaR1 |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 25124.85 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Q99720 |
|---|
| Residue: | 223 |
|---|
| Sequence: | MQWAVGRRWAWAALLLAVAAVLTQVVWLWLGTQSFVFQREEIAQLARQYAGLDHELAFSR
LIVELRRLHPGHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSRGHSGRY
WAEISDTIISGTFHQWREGTTKSEVFYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPS
TLAFALADTVFSTQDFLTLFYTLRSYARGLRLELTTYLFGQDP
|
|
|
|---|
| BDBM50334158 |
|---|
| n/a |
|---|
| Name | BDBM50334158 |
|---|
| Synonyms: | 1'-benzyl-3-(2-fluoroethyl)-3H-spiro[[2]benzofuran-1,4'-piperidine | CHEMBL1645202 | CHEMBL2314421 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C21H24FNO |
|---|
| Mol. Mass. | 325.4198 |
|---|
| SMILES | FCCC1OC2(CCN(Cc3ccccc3)CC2)c2ccccc12 |
|---|
| Structure | 
|
|---|
Search and Browse
