| Reaction Details |
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 | Report a problem with these data |
| Target | Laccase |
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| Ligand | BDBM50357700 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_786154 (CHEMBL1919988) |
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| IC50 | 4700±n/a nM |
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| Citation |  Dalisay, DS; Saludes, JP; Molinski, TF Ptilomycalin A inhibits laccase and melanization in Cryptococcus neoformans. Bioorg Med Chem19:6654-7 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Laccase |
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| Name: | Laccase |
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| Synonyms: | n/a |
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| Type: | PROTEIN |
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| Mol. Mass.: | 55472.53 |
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| Organism: | Trametes versicolor |
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| Description: | ChEMBL_786157 |
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| Residue: | 520 |
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| Sequence: | MSRFHSLLAFVVASLAAVAHAGIGPVADLTITNAAVSPDGFSRQAVVVNGGTPGPLITGN
MGDRFQLNVIDNLTDHTMLKSTSIHWHGFFQKGTNWADGPAFINQCPISSGHSFLYDFQV
PDQAGTFWYHSHLSTQYCDGLRGPFVVYDPNDPAADLYDVDNDDTVITLADWYHVAAKLG
PAFPLGADATLINGKGRSPSTTTADLTVISVTPGKRYRFRLVSLSCDPNHTFSIDGHNMT
IIETDSINTAPLVVDSIQIFAAQRYSFVLEANQAVDNYWIRANPSFGNVGFTGGINSAIL
RYDGAAAIEPTTTQTTSTEPLNEVNLHPLVATAVPGSPAAGGVDLAINMAFNFNGTNFFI
NGASFTPPTVPVLLQIISGAQNAQDLLPSGSVYSLPSNADIEISFPATAAAPGAPHPFHL
HGHAFAVVRSAGSTVYNYDNPIFRDVVSTGTPAAGDNVTIRFRTDNPGPWFLHCHIDFHL
EAGFAVVFAEDIPDVASANPVPQAWSDLCPTYDARDPSDQ
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| BDBM50357700 |
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| n/a |
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| Name | BDBM50357700 |
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| Synonyms: | PTILOMYCALIN A |
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| Type | Small organic molecule |
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| Emp. Form. | C45H83N6O5 |
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| Mol. Mass. | 788.1772 |
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| SMILES | CC[C@H]1CCCC[C@@]2(C[C@@H]3CC[C@@H]4[C@H](C(=O)OCCCCCCCCCCCCCCCC(=O)N(CCCN)CCCCN)[C@]5(CCC[C@@H](C)O5)NC(N2)=[N+]34)O1 |r,t:55| |
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| Structure | 
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