| Reaction Details |
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 | Report a problem with these data |
| Target | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 |
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| Ligand | BDBM50357882 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_787631 (CHEMBL1918084) |
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| Kd | 2200±n/a nM |
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| Citation |  Anraku, K; Inoue, T; Sugimoto, K; Kudo, K; Okamoto, Y; Morii, T; Mori, Y; Otsuka, M Design and synthesis of biotinylated inositol 1,3,4,5-tetrakisphosphate targeting Grp1 pleckstrin homology domain. Bioorg Med Chem19:6833-41 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 |
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| Name: | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 |
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| Synonyms: | PLC-III | PLC-delta-1 | PLCD1_RAT | Phosphoinositide phospholipase C-delta-1 | Phospholipase C-III | Phospholipase C-delta-1 | Plcd1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 85958.21 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_787631 |
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| Residue: | 756 |
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| Sequence: | MDSGRDFLTLHGLQDDPDLQALLKGSQLLKVKSSSWRRERFYKLQEDCKTIWQESRKVMR
SPESQLFSIEDIQEVRMGHRTEGLEKFARDIPEDRCFSIVFKDQRNTLDLIAPSPADAQH
WVQGLRKIIHHSGSMDQRQKLQHWIHSCLRKADKNKDNKMNFKELKDFLKELNIQVDDGY
ARKIFRECDHSQTDSLEDEEIETFYKMLTQRAEIDRAFEEAAGSAETLSVERLVTFLQHQ
QREEEAGPALALSLIERYEPSETAKAQRQMTKDGFLMYLLSADGNAFSLAHRRVYQDMDQ
PLSHYLVSSSHNTYLLEDQLTGPSSTEAYIRALCKGCRCLELDCWDGPNQEPIIYHGYTF
TSKILFCDVLRAIRDYAFKASPYPVILSLENHCSLEQQRVMARHLRAILGPILLDQPLDG
VTTSLPSPEQLKGKILLKGKKLGGLLPAGGENGSEATDVSDEVEAAEMEDEAVRSQVQHK
PKEDKLKLVPELSDMIIYCKSVHFGGFSSPGTSGQAFYEMASFSESRALRLLQESGNGFV
RHNVSCLSRIYPAGWRTDSSNYSPVEMWNGGCQIVALNFQTPGPEMDVYLGCFQDNGGCG
YVLKPAFLRDPNTTFNSRALTQGPWWRPERLRVRIISGQQLPKVNKNKNSIVDPKVIVEI
HGVGRDTGSRQTAVITNNGFNPRWDMEFEFEVTVPDLALVRFMVEDYDSSSKNDFIGQST
IPWNSLKQGYRHVHLLSKNGDQHPSATLFVKISIQD
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| BDBM50357882 |
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| n/a |
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| Name | BDBM50357882 |
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| Synonyms: | CHEMBL1916341 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H42N3O17P3S |
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| Mol. Mass. | 745.565 |
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| SMILES | O[C@@H]1[C@H](O)[C@@H](OP(O)(O)=O)[C@H](OP(O)(O)=O)[C@@H](O)[C@@H]1OP(O)(=O)OCCCCCCNC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12 |r| |
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| Structure | 
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