Search and Browse
Download
Enter Data
| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | C-C chemokine receptor type 2 | ||
| Ligand | BDBM50359103 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_789638 (CHEMBL1924723) | ||
| IC50 | >25000±n/a nM | ||
| Citation |  Lanter, JC; Markotan, TP; Zhang, X; Subasinghe, N; Kang, FA; Hou, C; Singer, M; Opas, E; McKenney, S; Crysler, C; Johnson, D; Molloy, CJ; Sui, Z The discovery of novel cyclohexylamide CCR2 antagonists. Bioorg Med Chem Lett21:7496-501 (2011) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| C-C chemokine receptor type 2 | |||
| Name: | C-C chemokine receptor type 2 | ||
| Synonyms: | C-C chemokine receptor type 2 (CCR2) | CCR2 | CCR2_HUMAN | CMKBR2 | Chemoattractant Cytokine Receptor 2 (CCR2) | Chemokine Receptor Type 2b (CCR2b) | Monocyte chemotactic protein-1 (MCP-1) | ||
| Type: | Enzyme | ||
| Mol. Mass.: | 41932.32 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P41597 | ||
| Residue: | 374 | ||
| Sequence: |
| ||
| BDBM50359103 | |||
| n/a | |||
| Name | BDBM50359103 | ||
| Synonyms: | CHEMBL1922812 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C28H36N4O | ||
| Mol. Mass. | 444.6116 | ||
| SMILES | NC(=O)C(NC1CCC(CC1)c1c[nH]c2ccccc12)C1CCN(Cc2ccccc2)CC1 |(9.11,-9.98,;10.45,-10.75,;11.78,-9.99,;10.44,-12.29,;9.11,-13.06,;9.11,-14.6,;7.77,-15.36,;7.76,-16.89,;9.09,-17.67,;10.43,-16.9,;10.44,-15.36,;9.09,-19.21,;7.84,-20.12,;8.32,-21.58,;9.86,-21.57,;10.89,-22.71,;12.39,-22.39,;12.86,-20.92,;11.83,-19.79,;10.34,-20.11,;11.77,-13.07,;11.76,-14.61,;13.08,-15.38,;14.42,-14.62,;15.75,-15.4,;17.09,-14.64,;18.41,-15.43,;19.75,-14.67,;19.76,-13.12,;18.43,-12.35,;17.09,-13.11,;14.43,-13.08,;13.1,-12.3,)| | ||
| Structure | 
| ||