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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | C-C chemokine receptor type 2 | ||
| Ligand | BDBM50359113 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_789638 (CHEMBL1924723) | ||
| IC50 | >25000±n/a nM | ||
| Citation |  Lanter, JC; Markotan, TP; Zhang, X; Subasinghe, N; Kang, FA; Hou, C; Singer, M; Opas, E; McKenney, S; Crysler, C; Johnson, D; Molloy, CJ; Sui, Z The discovery of novel cyclohexylamide CCR2 antagonists. Bioorg Med Chem Lett21:7496-501 (2011) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| C-C chemokine receptor type 2 | |||
| Name: | C-C chemokine receptor type 2 | ||
| Synonyms: | C-C chemokine receptor type 2 (CCR2) | CCR2 | CCR2_HUMAN | CMKBR2 | Chemoattractant Cytokine Receptor 2 (CCR2) | Chemokine Receptor Type 2b (CCR2b) | Monocyte chemotactic protein-1 (MCP-1) | ||
| Type: | Enzyme | ||
| Mol. Mass.: | 41932.32 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P41597 | ||
| Residue: | 374 | ||
| Sequence: |
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| BDBM50359113 | |||
| n/a | |||
| Name | BDBM50359113 | ||
| Synonyms: | CHEMBL1922802 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C28H29F3N4O2 | ||
| Mol. Mass. | 510.5507 | ||
| SMILES | NC(=O)C(NC1CCC(CC1)c1c[nH]c2ccccc12)C1CN(C1)C(=O)\C=C\c1cc(F)c(F)c(F)c1 |(38.72,-24.2,;40.06,-24.97,;41.39,-24.2,;40.05,-26.51,;38.72,-27.28,;38.72,-28.82,;37.38,-29.58,;37.37,-31.11,;38.7,-31.89,;40.04,-31.12,;40.05,-29.58,;38.7,-33.43,;37.45,-34.34,;37.93,-35.8,;39.47,-35.79,;40.5,-36.93,;42,-36.61,;42.47,-35.14,;41.44,-34.01,;39.95,-34.33,;41.38,-27.28,;41.78,-28.77,;43.27,-28.38,;42.87,-26.89,;44.6,-29.16,;44.59,-30.7,;45.94,-28.4,;47.26,-29.18,;48.6,-28.41,;48.6,-26.88,;49.94,-26.12,;49.94,-24.58,;51.27,-26.9,;52.61,-26.13,;51.26,-28.44,;52.59,-29.22,;49.93,-29.2,)| | ||
| Structure | 
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