| Reaction Details |
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 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 7 |
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| Ligand | BDBM50359419 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_793386 (CHEMBL1931940) |
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| Ki | 418±n/a nM |
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| Citation |  Marco, I; Valhondo, M; Martín-Fontecha, M; Vázquez-Villa, H; Del Río, J; Planas, A; Sagredo, O; Ramos, JA; Torrecillas, IR; Pardo, L; Frechilla, D; Benhamú, B; López-Rodríguez, ML New serotonin 5-HT(1A) receptor agonists with neuroprotective effect against ischemic cell damage. J Med Chem54:7986-99 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| 5-hydroxytryptamine receptor 7 |
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| Name: | 5-hydroxytryptamine receptor 7 |
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| Synonyms: | 5-HT-7 | 5-HT-X | 5-HT7 | 5-HT7L | 5-HT7S | 5-Hydroxytryptamine receptor 7 (5-HT7) | 5-hydroxytryptamine receptor 7 | 5-hydroxytryptamine receptor 7 (5-HT-7) | 5HT7R_RAT | Adrenergic Alpha | GPRFO | Htr7 | Serotonin (5-HT) receptor | Serotonin Receptor 7 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 49852.62 |
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| Organism: | Rattus norvegicus (rat) |
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| Description: | Rat cloned 5-HT7R. |
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| Residue: | 448 |
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| Sequence: | MMDVNSSGRPDLYGHLRSLILPEVGRGLQDLSPDGGAHPVVSSWMPHLLSGFLEVTASPA
PTWDAPPDNVSGCGEQINYGRVEKVVIGSILTLITLLTIAGNCLVVISVCFVKKLRQPSN
YLIVSLALADLSVAVAVMPFVSVTDLIGGKWIFGHFFCNVFIAMDVMCCTASIMTLCVIS
IDRYLGITRPLTYPVRQNGKCMAKMILSVWLLSASITLPPLFGWAQNVNDDKVCLISQDF
GYTIYSTAVAFYIPMSVMLFMYYQIYKAARKSAAKHKFPGFPRVQPESVISLNGVVKLQK
EVEECANLSRLLKHERKNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTS
CSCIPLWVERTCLWLGYANSLINPFIYAFFNRDLRTTYRSLLQCQYRNINRKLSAAGMHE
ALKLAERPERSEFVLQNSDHCGKKGHDT
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| BDBM50359419 |
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| n/a |
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| Name | BDBM50359419 |
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| Synonyms: | CHEMBL1926745 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H29N3O3 |
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| Mol. Mass. | 371.4733 |
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| SMILES | O=C1CN(CCCCNCC2CCc3ccccc3O2)C(=O)C2CCCN12 |
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| Structure | 
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