| Reaction Details |
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 | Report a problem with these data |
| Target | Carboxylic ester hydrolase |
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| Ligand | BDBM50359516 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_792863 (CHEMBL1931048) |
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| IC50 | 2720±n/a nM |
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| Citation |  Jiang, H; Wang, X; Huang, L; Luo, Z; Su, T; Ding, K; Li, X Benzenediol-berberine hybrids: multifunctional agents for Alzheimer's disease. Bioorg Med Chem19:7228-35 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Carboxylic ester hydrolase |
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| Name: | Carboxylic ester hydrolase |
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| Synonyms: | BuChE | Butyrlcholinesterase (BuChE) | Butyrylcholine esterase | Butyrylcholinesterase | Butyrylcholinesterase (BChE) | Butyrylcholinesterase (BuChE) | Butyrylcholinesterase (EqBuChE) | Carboxylic ester hydrolase | butyrylcholinesterase precursor |
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| Type: | Protein |
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| Mol. Mass.: | 68842.83 |
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| Organism: | Equus caballus (Horse) |
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| Description: | Q9N1N9 |
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| Residue: | 602 |
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| Sequence: | MQSWGTIICIRILLRFLLLWVLIGNSHTEEDIIITTKNGKVRGMNLPVLGGTVTAFLGIP
YAQPPLGRLRFKKPQSLTKWSNIWNATKYANSCYQNTDQSFPGFLGSEMWNPNTELSEDC
LYLNVWIPAPKPKNATVMIWIYGGGFQTGTSSLPVYDGKFLARVERVIVVSMNYRVGALG
FLALSENPEAPGNMGLFDQQLALQWVQKNIAAFGGNPRSVTLFGESAGAASVSLHLLSPR
SQPLFTRAILQSGSSNAPWAVTSLYEARNRTLTLAKRMGCSRDNETEMIKCLRDKDPQEI
LLNEVFVVPYDTLLSVNFGPTVDGDFLTDMPDTLLQLGQFKRTQILVGVNKDEGTAFLVY
GAPGFSKDNNSIITRKEFQEGLKIFFPRVSEFGRESILFHYMDWLDDQRAENYREALDDV
VGDYNIICPALEFTKKFSELGNDAFFYYFEHRSTKLPWPEWMGVMHGYEIEFVFGLPLER
RVNYTKAEEILSRSIMKRWANFAKYGNPNGTQSNSTRWPVFKSTEQKYLTLNTESPKVYT
KLRAQQCRFWTLFFPKVLELTGNIDEAEREWKAGFHRWNNYMMDWKNQFNDYTSKKESCS
DF
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| BDBM50359516 |
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| n/a |
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| Name | BDBM50359516 |
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| Synonyms: | CHEMBL1927136 |
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| Type | Small organic molecule |
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| Emp. Form. | C33H32N3O6 |
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| Mol. Mass. | 566.6231 |
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| SMILES | COc1ccc2[nH]cc(CCNC(=O)CCOc3c(OC)ccc4cc5-c6cc7OCOc7cc6CC[n+]5cc34)c2c1 |
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| Structure | 
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