Reaction Details |
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Target | Sigma non-opioid intracellular receptor 1 |
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Ligand | BDBM50419549 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_792210 (CHEMBL1930737) |
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Ki | 0.14±n/a nM |
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Citation | Ferorelli, S; Abate, C; Pedone, MP; Colabufo, NA; Contino, M; Perrone, R; Berardi, F Synthesis and binding assays of novel 3,3-dimethylpiperidine derivatives with various lipophilicities ass¿? receptor ligands. Bioorg Med Chem19:7612-22 (2011) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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Sigma non-opioid intracellular receptor 1 |
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Name: | Sigma non-opioid intracellular receptor 1 |
Synonyms: | OPRS1 | SGMR1_CAVPO | SIGMAR1 | Sigma 1-type opioid receptor | Sigma non-opioid intracellular receptor 1 | Sigma-1 receptor | Sigma1-receptor | Sigma1R | Sterol isomerase-like protein |
Type: | Protein |
Mol. Mass.: | 25307.17 |
Organism: | Cavia porcellus (Guinea pig) |
Description: | Q60492 |
Residue: | 223 |
Sequence: | MQWAVGRRWLWVALFLAAVAVLTQIVWLWLGTQNFVFQREEIAQLARQYAGLDHELAFSK
LIVELRRLHPVHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSPRHSGRY
WAEISDTIISGTFHQWREGTTKSEVFYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPS
TLGFALADTVFSTQDFLTLFYTLRVYARALQLELTTYLFGQDP
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BDBM50419549 |
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n/a |
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Name | BDBM50419549 |
Synonyms: | CHEMBL1929282 |
Type | Small organic molecule |
Emp. Form. | C22H35N |
Mol. Mass. | 313.52 |
SMILES | CC1(C)CCCN(CCCCC2CCCCc3ccccc23)C1 |
Structure |
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