| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Prostaglandin E2 receptor EP4 subtype |
|---|
| Ligand | BDBM50360164 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_793561 (CHEMBL1932312) |
|---|
| EC50 | 18±n/a nM |
|---|
| Citation |  Kambe, T; Maruyama, T; Nagase, T; Ogawa, S; Minamoto, C; Sakata, K; Maruyama, T; Nakai, H; Toda, M Synthesis and evaluation of novel modified¿-lactam prostanoids as EP4 subtype-selective agonists. Bioorg Med Chem20:702-13 (2012) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Prostaglandin E2 receptor EP4 subtype |
|---|
| Name: | Prostaglandin E2 receptor EP4 subtype |
|---|
| Synonyms: | PE2R4_RAT | Prostanoid EP4 receptor | Ptger4 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 53381.95 |
|---|
| Organism: | Rattus norvegicus |
|---|
| Description: | ChEMBL_1290039 |
|---|
| Residue: | 488 |
|---|
| Sequence: | MSIPGVNASFSSTPERLNSPVTIPAVMFIFGVVGNLVAIVVLCKSRKEQKETTFYTLVCG
LAVTDLLGTLLVSPVTIATYMKGQWPGDQALCDYSTFILLFFGLSGLSIICAMSIERYLA
INHAYFYSHYVDKRLAGLTLFAVYASNVLFCALPNMGLGRSERQYPGTWCFIDWTTNVTA
YAAFSYMYAGFSSFLILATVLCNVLVCGALLRMLRQFMRRTSLGTEQHHAAAAAAVASVA
CRGHAAASPALQRLSDFRRRRSFRRIAGAEIQMVILLIATSLVVLICSIPLVVRVFINQL
YQPSVVKDISRNPDLQAIRIASVNPILDPWIYILLRKTVLSKAIEKIKCLFCRIGGSGRD
GSAQHCSESRRTSSAMSGHSRSFLSRELREISSTSHTLLYLPDLTESSLGGKNLLPGTHG
MGLTQADTTSLRTLRISETSDSSQGQDSESVLLVDEVSGSQREEPASKGNSLQVTFPSET
LKLSEKCI
|
|
|
|---|
| BDBM50360164 |
|---|
| n/a |
|---|
| Name | BDBM50360164 |
|---|
| Synonyms: | CHEMBL1929531 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C21H29NO5S |
|---|
| Mol. Mass. | 407.524 |
|---|
| SMILES | CCc1cccc(C[C@H](O)\C=C\[C@H]2COC(=O)N2CCSCCCC(O)=O)c1 |r| |
|---|
| Structure | 
|
|---|
Search and Browse
