| Reaction Details |
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 | Report a problem with these data |
| Target | Prostaglandin E2 receptor EP4 subtype |
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| Ligand | BDBM50360173 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_793561 (CHEMBL1932312) |
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| EC50 | 2.4±n/a nM |
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| Citation |  Kambe, T; Maruyama, T; Nagase, T; Ogawa, S; Minamoto, C; Sakata, K; Maruyama, T; Nakai, H; Toda, M Synthesis and evaluation of novel modified¿-lactam prostanoids as EP4 subtype-selective agonists. Bioorg Med Chem20:702-13 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Prostaglandin E2 receptor EP4 subtype |
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| Name: | Prostaglandin E2 receptor EP4 subtype |
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| Synonyms: | PE2R4_RAT | Prostanoid EP4 receptor | Ptger4 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 53381.95 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_1290039 |
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| Residue: | 488 |
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| Sequence: | MSIPGVNASFSSTPERLNSPVTIPAVMFIFGVVGNLVAIVVLCKSRKEQKETTFYTLVCG
LAVTDLLGTLLVSPVTIATYMKGQWPGDQALCDYSTFILLFFGLSGLSIICAMSIERYLA
INHAYFYSHYVDKRLAGLTLFAVYASNVLFCALPNMGLGRSERQYPGTWCFIDWTTNVTA
YAAFSYMYAGFSSFLILATVLCNVLVCGALLRMLRQFMRRTSLGTEQHHAAAAAAVASVA
CRGHAAASPALQRLSDFRRRRSFRRIAGAEIQMVILLIATSLVVLICSIPLVVRVFINQL
YQPSVVKDISRNPDLQAIRIASVNPILDPWIYILLRKTVLSKAIEKIKCLFCRIGGSGRD
GSAQHCSESRRTSSAMSGHSRSFLSRELREISSTSHTLLYLPDLTESSLGGKNLLPGTHG
MGLTQADTTSLRTLRISETSDSSQGQDSESVLLVDEVSGSQREEPASKGNSLQVTFPSET
LKLSEKCI
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| BDBM50360173 |
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| n/a |
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| Name | BDBM50360173 |
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| Synonyms: | CHEMBL1929544 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H29NO5S2 |
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| Mol. Mass. | 439.589 |
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| SMILES | COCc1cccc(C[C@H](O)\C=C\[C@H]2CSC(=O)N2CCSCCCC(O)=O)c1 |r| |
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| Structure | 
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