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TargetSphingosine 1-phosphate receptor 1
LigandBDBM50360522
Substrate/Competitorn/a
Meas. Tech.ChEMBL_796733
EC50>100000±n/a nM
Citation He XWang LZheng ZXiao JZhong WLi S Novel immunomodulators based on an oxazolin-2-one-4-carboxamide scaffold. Bioorg Med Chem Lett 22:553-7 (2011) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Sphingosine 1-phosphate receptor 1
Name:Sphingosine 1-phosphate receptor
Synonyms:CHEDG1 | EDG1 | Endothelial differentiation G-protein coupled receptor 1 | S1P receptor | S1P1 | S1PR1 | Sphingosine 1-phosphate receptor 1 (S1PR1) | Sphingosine 1-phosphate receptor Edg-1
Type:Enzyme
Mol. Mass.:42836.02
Organism:Homo sapiens (Human)
Description:P21453
Residue:382
Sequence:
MGPTSVPLVKAHRSSVSDYVNYDIIVRHYNYTGKLNISADKENSIKLTSVVFILICCFII
LENIFVLLTIWKTKKFHRPMYYFIGNLALSDLLAGVAYTANLLLSGATTYKLTPAQWFLR
EGSMFVALSASVFSLLAIAIERYITMLKMKLHNGSNNFRLFLLISACWVISLILGGLPIM
GWNCISALSSCSTVLPLYHKHYILFCTTVFTLLLLSIVILYCRIYSLVRTRSRRLTFRKN
ISKASRSSEKSLALLKTVIIVLSVFIACWAPLFILLLLDVGCKVKTCDILFRAEYFLVLA
VLNSGTNPIIYTLTNKEMRRAFIRIMSCCKCPSGDSAGKFKRPIIAGMEFSRSKSDNSSH
PQKDEGDNPETIMSSGNVNSSS
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  Blast E-value cutoff:
BDBM50360522
n/a
NameBDBM50360522
Synonyms:CHEMBL1935662
TypeSmall organic molecule
Emp. Form.C19H19ClN2O4
Mol. Mass.374.818
SMILESNC(=O)C1(CCc2ccc(OCc3ccccc3Cl)cc2)COC(=O)N1
Structure
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