| Reaction Details |
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 | Report a problem with these data |
| Target | 40S ribosomal protein S27 |
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| Ligand | BDBM50361088 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_795099 (CHEMBL1936525) |
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| IC50 | >10000±n/a nM |
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| Citation |  Caruso, M; Valsasina, B; Ballinari, D; Bertrand, J; Brasca, MG; Caldarelli, M; Cappella, P; Fiorentini, F; Gianellini, LM; Scolaro, A; Beria, I 5-(2-amino-pyrimidin-4-yl)-1H-pyrrole and 2-(2-amino-pyrimidin-4-yl)-1,5,6,7-tetrahydro-pyrrolo[3,2-c]pyridin-4-one derivatives as new classes of selective and orally available Polo-like kinase 1 inhibitors. Bioorg Med Chem Lett22:96-101 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| 40S ribosomal protein S27 |
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| Name: | 40S ribosomal protein S27 |
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| Synonyms: | MPS-1 | MPS1 | Metallopan-stimulin 1 | RPS27 | RS27_HUMAN |
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| Type: | PROTEIN |
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| Mol. Mass.: | 9472.13 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1446775 |
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| Residue: | 84 |
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| Sequence: | MPLAKDLLHPSPEEEKRKHKKKRLVQSPNSYFMDVKCPGCYKITTVFSHAQTVVLCVGCS
TVLCQPTGGKARLTEGCSFRRKQH
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| BDBM50361088 |
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| n/a |
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| Name | BDBM50361088 |
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| Synonyms: | CHEMBL1933582 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H26F3N7O2 |
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| Mol. Mass. | 501.5041 |
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| SMILES | CN1CCN(CC1)c1ccc(OC(F)(F)F)c(Nc2nccc(n2)-c2cc3c(CCNC3=O)n2C)c1 |
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| Structure | 
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