| Reaction Details |
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 | Report a problem with these data |
| Target | dTDP-4-dehydrorhamnose reductase |
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| Ligand | BDBM50180512 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_799072 (CHEMBL1942013) |
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| IC50 | 25000±n/a nM |
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| Citation |  Wang, Y; Hess, TN; Jones, V; Zhou, JZ; McNeil, MR; Andrew McCammon, J Novel inhibitors of Mycobacterium tuberculosis dTDP-6-deoxy-L-lyxo-4-hexulose reductase (RmlD) identified by virtual screening. Bioorg Med Chem Lett21:7064-7 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| dTDP-4-dehydrorhamnose reductase |
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| Name: | dTDP-4-dehydrorhamnose reductase |
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| Synonyms: | RMLD_MYCTU | dTDP-4-keto-L-rhamnose reductase | dTDP-6-deoxy-L-lyxo-4-hexulose reductase | dTDP-6-deoxy-L-mannose dehydrogenase | dTDP-L-rhamnose synthase | rmlD |
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| Type: | PROTEIN |
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| Mol. Mass.: | 32045.92 |
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| Organism: | Mycobacterium tuberculosis |
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| Description: | ChEMBL_799072 |
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| Residue: | 304 |
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| Sequence: | MAGRSERLVITGAGGQLGSHLTAQAAREGRDMLALTSSQWDITDPAAAERIIRHGDVVIN
CAAYTDVDGAESNEAVAYAVNATGPQHLARACARVGARLIHVSTDYVFDGDFGGAEPRPY
EPTDETAPQGVYARSKLAGEQAVLAAFPEAAVVRTAWVYTGGTGKDFVAVMRRLAAGHGR
VDVVDDQTGSPTYVADLAEALLALADAGVRGRVLHAANEGVVSRFGQARAVFEECGADPQ
RVRPVSSAQFPRPAPRSSYSALSSRQWALAGLTPLRHWRSALATALAAPANSTSIDRRLP
STRD
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| BDBM50180512 |
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| n/a |
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| Name | BDBM50180512 |
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| Synonyms: | 1-methyl-5-vinyl-9,10-dihydrophenanthrene-2,7-diol | CHEMBL205119 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H16O2 |
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| Mol. Mass. | 252.3077 |
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| SMILES | Cc1c(O)ccc-2c1CCc1cc(O)cc(C=C)c-21 |
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| Structure | 
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