| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Amine oxidase [flavin-containing] B |
|---|
| Ligand | BDBM50361607 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_799140 (CHEMBL1942124) |
|---|
| Ki | 200000±n/a nM |
|---|
| Citation |  Valente, S; Tomassi, S; Tempera, G; Saccoccio, S; Agostinelli, E; Mai, A Novel reversible monoamine oxidase A inhibitors: highly potent and selective 3-(1H-pyrrol-3-yl)-2-oxazolidinones. J Med Chem54:8228-32 (2011) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Amine oxidase [flavin-containing] B |
|---|
| Name: | Amine oxidase [flavin-containing] B |
|---|
| Synonyms: | AOFB_BOVIN | Amine oxidase [flavin-containing] B | MAO-B | MAOB | Monoamine Oxidase Type B (MAO-B) | Monoamine oxidase | Monoamine oxidase B | Monoamine oxidase type B |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 58428.94 |
|---|
| Organism: | Bos taurus |
|---|
| Description: | ChEMBL_1501478 |
|---|
| Residue: | 520 |
|---|
| Sequence: | MSSKCDVVVVGGGISGMAAAKLLHDSGLNVIVLEARDRVGGRTYTLRNQKVKYVDLGGSY
VGPTQNHILRLSKELGLETYKVNEVERLIHHTKGKSYPFRGSFPSVWNPITYLDHNNLWR
TMDDMGREIPSDAPWKAPLAEQWDLMTMKELLDKICWTESSKQLAILFVNLCVTAEIHEV
SALWFLWYVKQCGGTTRIFSTSNGGQERKFVGGSGQVSERIMDLLGDRVKLERPVIHIDQ
TGENVLVETLNHELYEAKYVISAVPPVLGMKIHFNPPLPMMRNQLITRVPLGSVIKSIVY
YKEPFWRNMDYCGSMIIEGEEAPVAYALDDTKPDGSYPAIIGFILAHKARKLARLTKEER
LKKLCDLYAKVLGSQEALHPVHYEEKNWCEEQYSGGCYTSYFPPGIMTQYGRVLRQPVGR
IYFAGTETATHWSGYMEGAVEAGERAAREILHAMGKIPEDEIWLPEPESVDVPAKPITTT
FLQRHLPSVPGLLKLIGLTTIFSATALGFLAHKRGLLVRI
|
|
|
|---|
| BDBM50361607 |
|---|
| n/a |
|---|
| Name | BDBM50361607 |
|---|
| Synonyms: | CHEMBL1938411 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C12H16N2O3 |
|---|
| Mol. Mass. | 236.267 |
|---|
| SMILES | COC[C@H]1CN(C(=O)O1)c1ccn(CC=C)c1 |r| |
|---|
| Structure | 
|
|---|
Search and Browse
