| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Estrogen receptor beta |
|---|
| Ligand | BDBM50364076 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_803011 (CHEMBL1954168) |
|---|
| Ki | 0.27±n/a nM |
|---|
| Citation |  Carroll, VM; Jeyakumar, M; Carlson, KE; Katzenellenbogen, JA Diarylpropionitrile (DPN) enantiomers: synthesis and evaluation of estrogen receptorß-selective ligands. J Med Chem55:528-37 (2012) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Estrogen receptor beta |
|---|
| Name: | Estrogen receptor beta |
|---|
| Synonyms: | ESR2_RAT | Erbeta | Esr2 | Estrogen receptor | Estrogen receptor beta | Nr3a2 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 59173.80 |
|---|
| Organism: | Rattus norvegicus |
|---|
| Description: | ChEMBL_803011 |
|---|
| Residue: | 530 |
|---|
| Sequence: | MEIKNSPSSLSSPASYNCSQSILPLEHGPIYIPSSYVDNRHEYSAMTFYSPAVMNYSVPG
STSNLDGGPVRLSTSPNVLWPTSGHLSPLATHCQSSLLYAEPQKSPWCEARSLEHTLPVN
RETLKRKLSGSSCASPVTSPNAKRDAHFCPVCSDYASGYHYGVWSCEGCKAFFKRSIQGH
NDYICPATNQCTIDKNRRKSCQACRLRKCYEVGMVKCGSRRERCGYRIVRRQRSSSEQVH
CLSKAKRNGGHAPRVKELLLSTLSPEQLVLTLLEAEPPNVLVSRPSMPFTEASMMMSLTK
LADKELVHMIGWAKKIPGFVELSLLDQVRLLESCWMEVLMVGLMWRSIDHPGKLIFAPDL
VLDRDEGKCVEGILEIFDMLLATTSRFRELKLQHKEYLCVKAMILLNSSMYPLASANQEA
ESSRKLTHLLNAVTDALVWVIAKSGISSQQQSVRLANLLMLLSHVRHISNKGMEHLLSMK
CKNVVPVYDLLLEMLNAHTLRGYKSSISGSECSSTEDSKNKESSQNLQSQ
|
|
|
|---|
| BDBM50364076 |
|---|
| n/a |
|---|
| Name | BDBM50364076 |
|---|
| Synonyms: | CHEMBL198159 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C15H13NO2 |
|---|
| Mol. Mass. | 239.2692 |
|---|
| SMILES | Oc1ccc(C[C@@H](C#N)c2ccc(O)cc2)cc1 |
|---|
| Structure | 
|
|---|
Search and Browse
