| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Amine oxidase [flavin-containing] B |
|---|
| Ligand | BDBM50364461 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_802417 (CHEMBL1954860) |
|---|
| Ki | 2950±n/a nM |
|---|
| Citation |  Song, B; Xiao, T; Qi, X; Li, LN; Qin, K; Nian, S; Hu, GX; Yu, Y; Liang, G; Ye, F Design and synthesis of 8-substituted benzamido-phenylxanthine derivatives as MAO-B inhibitors. Bioorg Med Chem Lett22:1739-42 (2012) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Amine oxidase [flavin-containing] B |
|---|
| Name: | Amine oxidase [flavin-containing] B |
|---|
| Synonyms: | AOFB_MOUSE | Amine oxidase [flavin-containing] B | MAO-B | Maob | Monoamine Oxidase Type B (MAO-B) | Monoamine oxidase | Monoamine oxidase type B |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 58568.67 |
|---|
| Organism: | Mus musculus |
|---|
| Description: | ChEMBL_605809 |
|---|
| Residue: | 520 |
|---|
| Sequence: | MSNKSDVIVVGGGISGMAAAKLLHDCGLSVVVLEARDRVGGRTYTIRNKNVKYVDLGGSY
VGPTQNRILRLAKELGLETYKVNEVERLIHFVKGKSYAFRGPFPPVWNPITYLDNNNLWR
TMDEMGQEIPSDAPWKAPLAEEWDYMTMKELLDKICWTKSTKQIATLFVNLCVTAETHEV
SALWFLWYVKQCGGTTRIISTTNGGQERKFIGGSGQVSERIKDILGDRVKLERPVIHIDQ
TGENVIVKTLNHEIYEAKYVISAIPPALGMKIHYSPPLPMLRNQLISRVPLGSVIKCMVY
YKEPFWRKKDFCGTMVIEGEEAPIAYTLDDTKPDGTYAAIMGFILAHKARKLVRLTKEER
LRKLCELYAKVLNSQEALQPVHYEEKNWCEEQYSGGCYTTYFPPGILTQYGRVLRQPVGK
IFFAGTETASHWSGYMEGAVEAGERAAREILHAIGKIPEDEIWQPEPESLDVPARPITST
FLERHLPSVPGLLKLFGLTTILSATALGFLAHKRGLFVHF
|
|
|
|---|
| BDBM50364461 |
|---|
| n/a |
|---|
| Name | BDBM50364461 |
|---|
| Synonyms: | CHEMBL1950688 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C21H19N5O3 |
|---|
| Mol. Mass. | 389.4073 |
|---|
| SMILES | Cn1c(nc2n(C)c(=O)n(C)c(=O)c12)-c1cccc(NC(=O)c2ccccc2)c1 |
|---|
| Structure | 
|
|---|
Search and Browse
