| Reaction Details |
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 | Report a problem with these data |
| Target | Carboxypeptidase A1 |
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| Ligand | BDBM50365329 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_806484 (CHEMBL1959523) |
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| IC50 | 4500±n/a nM |
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| Citation |  Cheruku, P; Plaza, A; Lauro, G; Keffer, J; Lloyd, JR; Bifulco, G; Bewley, CA Discovery and synthesis of namalide reveals a new anabaenopeptin scaffold and peptidase inhibitor. J Med Chem55:735-42 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Carboxypeptidase A1 |
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| Name: | Carboxypeptidase A1 |
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| Synonyms: | CBPA1_BOVIN | CPA | CPA1 | Carboxypeptidase A | Carboxypeptidase A (CPA) | Carboxypeptidase A1 precursor |
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| Type: | Enzyme |
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| Mol. Mass.: | 47073.90 |
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| Organism: | Bos taurus (bovine) |
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| Description: | From Sigma-Aldrich Co. |
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| Residue: | 419 |
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| Sequence: | MQGLLILSVLLGAALGKEDFVGHQVLRITAADEAEVQTVKELEDLEHLQLDFWRGPGQPG
SPIDVRVPFPSLQAVKVFLEAHGIRYRIMIEDVQSLLDEEQEQMFASQSRARSTNTFNYA
TYHTLDEIYDFMDLLVAEHPQLVSKLQIGRSYEGRPIYVLKFSTGGSNRPAIWIDLGIHS
REWITQATGVWFAKKFTEDYGQDPSFTAILDSMDIFLEIVTNPDGFAFTHSQNRLWRKTR
SVTSSSLCVGVDANRNWDAGFGKAGASSSPCSETYHGKYANSEVEVKSIVDFVKDHGNFK
AFLSIHSYSQLLLYPYGYTTQSIPDKTELNQVAKSAVEALKSLYGTSYKYGSIITTIYQA
SGGSIDWSYNQGIKYSFTFELRDTGRYGFLLPASQIIPTAQETWLGVLTIMEHTLNNLY
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| BDBM50365329 |
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| n/a |
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| Name | BDBM50365329 |
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| Synonyms: | CHEMBL1955931 |
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| Type | Small organic molecule |
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| Emp. Form. | C31H44N6O6 |
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| Mol. Mass. | 596.7177 |
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| SMILES | CC[C@H](C)[C@H](NC(=O)[C@@H](CCCCN)NC(=O)N[C@@H](Cc1ccccc1)C(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O |r| |
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| Structure | 
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