| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Prostaglandin E2 receptor EP4 subtype |
|---|
| Ligand | BDBM50360624 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_808316 (CHEMBL1961333) |
|---|
| Ki | 35±n/a nM |
|---|
| Citation |  Kambe, T; Maruyama, T; Nakai, Y; Yoshida, H; Oida, H; Maruyama, T; Abe, N; Nishiura, A; Nakai, H; Toda, M Discovery of novel prostaglandin analogs as potent and selective EP2/EP4 dual agonists. Bioorg Med Chem20:2235-51 (2012) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Prostaglandin E2 receptor EP4 subtype |
|---|
| Name: | Prostaglandin E2 receptor EP4 subtype |
|---|
| Synonyms: | PE2R4_MOUSE | PGE receptor, EP4 subtype | Prostanoid EP4 receptor | Ptger4 | Ptgerep4 |
|---|
| Type: | G-protein coupled receptor |
|---|
| Mol. Mass.: | 56175.66 |
|---|
| Organism: | Mus musculus (Mouse) |
|---|
| Description: | n/a |
|---|
| Residue: | 513 |
|---|
| Sequence: | MAEVGGTIPRSNRELQRCVLLTTTIMSIPGVNASFSSTPERLNSPVTIPAVMFIFGVVGN
LVAIVVLCKSRKEQKETTFYTLVCGLAVTDLLGTLLVSPVTIATYMKGQWPGDQALCDYS
TFILLFFGLSGLSIICAMSIERYLAINHAYFYSHYVDKRLAGLTLFAIYASNVLFCALPN
MGLGRSERQYPGTWCFIDWTTNVTAYAAFSYMYAGFSSFLILATVLCNVLVCGALLRMHR
QFMRRTSLGTEQHHAAAAAAVASVACRGHAGASPALQRLSDFRRRRSFRRIAGAEIQMVI
LLIATSLVVLICSIPLVVRVFINQLYQPNVVKDISRNPDLQAIRIASVNPILDPWIYILL
RKTVLSKAIEKIKCLFCRIGGSGRDSSAQHCSESRRTSSAMSGHSRSFLARELKEISSTS
QTLLYLPDLTESSLGGRNLLPGSHGMGLTQADTTSLRTLRISETSDSSQGQDSESVLLVD
EVSGSHREEPASKGNSLQVTFPSETLKLSEKCI
|
|
|
|---|
| BDBM50360624 |
|---|
| n/a |
|---|
| Name | BDBM50360624 |
|---|
| Synonyms: | CHEMBL1933720 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C22H26N2O5 |
|---|
| Mol. Mass. | 398.4522 |
|---|
| SMILES | Cc1cccc(C[C@H](O)\C=C\[C@H]2CCC(=O)N2CCCc2nc(co2)C(O)=O)c1 |r| |
|---|
| Structure | 
|
|---|
Search and Browse
