| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Prostaglandin E2 receptor EP4 subtype |
|---|
| Ligand | BDBM50366138 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_808318 (CHEMBL1960894) |
|---|
| EC50 | 480±n/a nM |
|---|
| Citation |  Kambe, T; Maruyama, T; Nakai, Y; Yoshida, H; Oida, H; Maruyama, T; Abe, N; Nishiura, A; Nakai, H; Toda, M Discovery of novel prostaglandin analogs as potent and selective EP2/EP4 dual agonists. Bioorg Med Chem20:2235-51 (2012) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Prostaglandin E2 receptor EP4 subtype |
|---|
| Name: | Prostaglandin E2 receptor EP4 subtype |
|---|
| Synonyms: | PE2R4_RAT | Prostanoid EP4 receptor | Ptger4 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 53381.95 |
|---|
| Organism: | Rattus norvegicus |
|---|
| Description: | ChEMBL_1290039 |
|---|
| Residue: | 488 |
|---|
| Sequence: | MSIPGVNASFSSTPERLNSPVTIPAVMFIFGVVGNLVAIVVLCKSRKEQKETTFYTLVCG
LAVTDLLGTLLVSPVTIATYMKGQWPGDQALCDYSTFILLFFGLSGLSIICAMSIERYLA
INHAYFYSHYVDKRLAGLTLFAVYASNVLFCALPNMGLGRSERQYPGTWCFIDWTTNVTA
YAAFSYMYAGFSSFLILATVLCNVLVCGALLRMLRQFMRRTSLGTEQHHAAAAAAVASVA
CRGHAAASPALQRLSDFRRRRSFRRIAGAEIQMVILLIATSLVVLICSIPLVVRVFINQL
YQPSVVKDISRNPDLQAIRIASVNPILDPWIYILLRKTVLSKAIEKIKCLFCRIGGSGRD
GSAQHCSESRRTSSAMSGHSRSFLSRELREISSTSHTLLYLPDLTESSLGGKNLLPGTHG
MGLTQADTTSLRTLRISETSDSSQGQDSESVLLVDEVSGSQREEPASKGNSLQVTFPSET
LKLSEKCI
|
|
|
|---|
| BDBM50366138 |
|---|
| n/a |
|---|
| Name | BDBM50366138 |
|---|
| Synonyms: | CHEMBL1957437 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C30H28N2O4S2 |
|---|
| Mol. Mass. | 544.684 |
|---|
| SMILES | O[C@@H](Cc1cccc(c1)-c1ccc2ccccc2c1)\C=C\[C@H]1CCC(=O)N1CCSc1nc(cs1)C(O)=O |r| |
|---|
| Structure | 
|
|---|
Search and Browse
