| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Adenosine receptor A2a/A2b |
|---|
| Ligand | BDBM50366244 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_30560 (CHEMBL649872) |
|---|
| Ki | 15000±n/a nM |
|---|
| Citation |  Nair, V; Fesbender, AJ; Miller, LP; Bruce, JL High selectivity of novel isoguanosine analogues for the adenosine A1 receptor Bioorg Med Chem Lett1:481-486 (1991) Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Adenosine receptor A2a/A2b |
|---|
| Name: | Adenosine receptor A2a/A2b |
|---|
| Synonyms: | Adenosine A2 receptor |
|---|
| Type: | n/a |
|---|
| Mol. Mass.: | n/a |
|---|
| Description: | ASSAY_ID of ChEMBL is 30560 |
|---|
| Components: | This complex has 2 components. |
|---|
| Component 1 |
| Name: | Adenosine receptor A2b |
|---|
| Synonyms: | AA2BR_RAT | Adenosine receptor | Adora2b |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 36378.84 |
|---|
| Organism: | Rattus norvegicus |
|---|
| Description: | ChEMBL_32934 |
|---|
| Residue: | 332 |
|---|
| Sequence: | MQLETQDALYVALELVIAALAVAGNVLVCAAVGASSALQTPTNYFLVSLATADVAVGLFA
IPFAITISLGFCTDFHSCLFLACFVLVLTQSSIFSLLAVAVDRYLAIRVPLRYKGLVTGT
RARGIIAVLWVLAFGIGLTPFLGWNSKDRATSNCTEPGDGITNKSCCPVKCLFENVVPMS
YMVYFNFFGCVLPPLLIMMVIYIKIFMVACKQLQHMELMEHSRTTLQREIHAAKSLAMIV
GIFALCWLPVHAINCITLFHPALAKDKPKWVMNVAILLSHANSVVNPIVYAYRNRDFRYS
FHRIISRYVLCQTDTKGGSGQAGGQSTFSLSL
|
|
|
|---|
| Component 2 |
| Name: | Adenosine receptor A2a |
|---|
| Synonyms: | AA2AR_RAT | ADENOSINE A2a | Adenosine A2 receptor | Adenosine A2a receptor (A2a) | Adenosine Receptors A2a (A2a) | Adenosine receptor A2a and A3 | Adenosine receptors A2a | Adora2a | Rat striatal adenosine A2a receptor |
|---|
| Type: | G Protein-Coupled Receptor (GPCR) |
|---|
| Mol. Mass.: | 45015.65 |
|---|
| Organism: | Rattus norvegicus (rat) |
|---|
| Description: | Rat A2A receptors expressed in CHO cells. |
|---|
| Residue: | 410 |
|---|
| Sequence: | MGSSVYITVELAIAVLAILGNVLVCWAVWINSNLQNVTNFFVVSLAAADIAVGVLAIPFA
ITISTGFCAACHGCLFFACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGVRAKG
IIAICWVLSFAIGLTPMLGWNNCSQKDGNSTKTCGEGRVTCLFEDVVPMNYMVYYNFFAF
VLLPLLLMLAIYLRIFLAARRQLKQMESQPLPGERTRSTLQKEVHAAKSLAIIVGLFALC
WLPLHIINCFTFFCSTCRHAPPWLMYLAIILSHSNSVVNPFIYAYRIREFRQTFRKIIRT
HVLRRQEPFQAGGSSAWALAAHSTEGEQVSLRLNGHPLGVWANGSATHSGRRPNGYTLGL
GGGGSAQGSPRDVELPTQERQEGQEHPGLRGHLVQARVGASSWSSEFAPS
|
|
|
|---|
| BDBM50366244 |
|---|
| n/a |
|---|
| Name | BDBM50366244 |
|---|
| Synonyms: | CHEMBL608445 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C14H19N5O5 |
|---|
| Mol. Mass. | 337.3312 |
|---|
| SMILES | OC[C@H]1OC([C@H](O)[C@@H]1O)n1cnc2c(NC3CCC3)[nH]c(=O)nc12 |r| |
|---|
| Structure | 
|
|---|
Search and Browse
