| Reaction Details |
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 | Report a problem with these data |
| Target | Muscarinic acetylcholine receptor M1 |
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| Ligand | BDBM50280549 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_139646 |
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| Ki | 1750±n/a nM |
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| Citation |  Shapiro, G; Floersheim, P; Amstutz, R; Boddeke, H; Bolliger, G; Cottens, S; Enz, A; Gmelin, G; Gull, P; Supavilai, P Muscarinic agonist SAR of azaspirodioxolanes Bioorg Med Chem Lett2:815-820 (1992) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Muscarinic acetylcholine receptor M1 |
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| Name: | Muscarinic acetylcholine receptor M1 |
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| Synonyms: | ACM1_RAT | Cholinergic, muscarinic M1 | Chrm-1 | Chrm1 | cholinergic receptor, muscarinic 1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 51390.46 |
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| Organism: | RAT |
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| Description: | P08482 |
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| Residue: | 460 |
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| Sequence: | MNTSVPPAVSPNITVLAPGKGPWQVAFIGITTGLLSLATVTGNLLVLISFKVNTELKTVN
NYFLLSLACADLIIGTFSMNLYTTYLLMGHWALGTLACDLWLALDYVASNASVMNLLLIS
FDRYFSVTRPLSYRAKRTPRRAALMIGLAWLVSFVLWAPAILFWQYLVGERTVLAGQCYI
QFLSQPIITFGTAMAAFYLPVTVMCTLYWRIYRETENRARELAALQGSETPGKGGGSSSS
SERSQPGAEGSPESPPGRCCRCCRAPRLLQAYSWKEEEEEDEGSMESLTSSEGEEPGSEV
VIKMPMVDSEAQAPTKQPPKSSPNTVKRPTKKGRDRGGKGQKPRGKEQLAKRKTFSLVKE
KKAARTLSAILLAFILTWTPYNIMVLVSTFCKDCVPETLWELGYWLCYVNSTVNPMCYAL
CNKAFRDTFRLLLLCRWDKRRWRKIPKRPGSVHRTPSRQC
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| BDBM50280549 |
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| n/a |
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| Name | BDBM50280549 |
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| Synonyms: | (Trans)-(R)-2,7-Dimethyl-1,3-dioxa-7-aza-spiro[4.4]nonane | CHEMBL167501 |
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| Type | Small organic molecule |
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| Emp. Form. | C8H15NO2 |
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| Mol. Mass. | 157.2102 |
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| SMILES | C[C@@H]1OCC2(CCN(C)C2)O1 |
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| Structure | 
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