| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Muscarinic acetylcholine receptor M1 |
|---|
| Ligand | BDBM50067479 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_139646 |
|---|
| Ki | 1850±n/a nM |
|---|
| Citation |  Shapiro, G; Floersheim, P; Amstutz, R; Boddeke, H; Bolliger, G; Cottens, S; Enz, A; Gmelin, G; Gull, P; Supavilai, P Muscarinic agonist SAR of azaspirodioxolanes Bioorg Med Chem Lett2:815-820 (1992) Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Muscarinic acetylcholine receptor M1 |
|---|
| Name: | Muscarinic acetylcholine receptor M1 |
|---|
| Synonyms: | ACM1_RAT | Cholinergic, muscarinic M1 | Chrm-1 | Chrm1 | cholinergic receptor, muscarinic 1 |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 51390.46 |
|---|
| Organism: | RAT |
|---|
| Description: | P08482 |
|---|
| Residue: | 460 |
|---|
| Sequence: | MNTSVPPAVSPNITVLAPGKGPWQVAFIGITTGLLSLATVTGNLLVLISFKVNTELKTVN
NYFLLSLACADLIIGTFSMNLYTTYLLMGHWALGTLACDLWLALDYVASNASVMNLLLIS
FDRYFSVTRPLSYRAKRTPRRAALMIGLAWLVSFVLWAPAILFWQYLVGERTVLAGQCYI
QFLSQPIITFGTAMAAFYLPVTVMCTLYWRIYRETENRARELAALQGSETPGKGGGSSSS
SERSQPGAEGSPESPPGRCCRCCRAPRLLQAYSWKEEEEEDEGSMESLTSSEGEEPGSEV
VIKMPMVDSEAQAPTKQPPKSSPNTVKRPTKKGRDRGGKGQKPRGKEQLAKRKTFSLVKE
KKAARTLSAILLAFILTWTPYNIMVLVSTFCKDCVPETLWELGYWLCYVNSTVNPMCYAL
CNKAFRDTFRLLLLCRWDKRRWRKIPKRPGSVHRTPSRQC
|
|
|
|---|
| BDBM50067479 |
|---|
| n/a |
|---|
| Name | BDBM50067479 |
|---|
| Synonyms: | 2'-methyl-(2'S)-spiro[4-azabicyclo[2.2.1]heptane-2,4'-(dihydro[1,3]dioxolane)] | Azaspirodioxolane analogue | CHEMBL134830 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C9H15NO2 |
|---|
| Mol. Mass. | 169.2209 |
|---|
| SMILES | C[C@H]1OCC2(CN3CCC2C3)O1 |TLB:3:4:10:8.7,THB:11:4:10:8.7| |
|---|
| Structure | 
|
|---|
Search and Browse
