| Reaction Details |
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 | Report a problem with these data |
| Target | Kappa-type opioid receptor |
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| Ligand | BDBM50281811 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_146528 |
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| Ki | >10000±n/a nM |
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| Citation |  Cain, GA; Christos, TE; Johnson, AL; Pottorf, RS; Confalone, PN; William Tam, S; Schmidt, WK Neurotensin receptor binding and antinociceptive activity for lipophilic N-amido neurotensin(913) analogs Bioorg Med Chem Lett3:2055-2060 (1993) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Kappa-type opioid receptor |
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| Name: | Kappa-type opioid receptor |
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| Synonyms: | Kappa Opioid Receptor | OPIATE Kappa | OPRK1 | OPRK_CAVPO | Opiate Kappa 1 | mu/kappa opioid receptor |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 42744.99 |
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| Organism: | Cavia porcellus (domestic guinea pig) |
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| Description: | P41144 |
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| Residue: | 380 |
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| Sequence: | MGRRRQGPAQPASELPARNACLLPNGSAWLPGWAEPDGNGSAGPQDEQLEPAHISPAIPV
IITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSTVYL
MNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINI
CIWLLSSSVGISAIILGGTKVREDVDIIECSLQFPDDDYSWWDLFMKICVFVFAFVIPVL
IIIVCYTLMILRLKSVRLLSGSREKDRNLRRITRLVLVVVAVFIICWTPIHIFILVEALG
STSHSTAALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFPIKMRMERQSTSRV
RNTVQDPAYMRNVDGVNKPV
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| BDBM50281811 |
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| n/a |
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| Name | BDBM50281811 |
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| Synonyms: | (S)-2-{(2S,3S)-2-[(S)-2-[((S)-1-{(S)-2-[(Adamantane-1-carbonyl)-amino]-6-amino-hexanoyl}-pyrrolidine-2-carbonyl)-amino]-3-(4-hydroxy-phenyl)-propionylamino]-3-methyl-pentanoylamino}-4-methyl-pentanoic acid | CHEMBL2372106 |
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| Type | Small organic molecule |
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| Emp. Form. | C43H66N6O8 |
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| Mol. Mass. | 795.0195 |
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| SMILES | CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCCN)NC(=O)C12CC3CC(CC(C3)C1)C2)C(=O)N[C@@H](CC(C)C)C(O)=O |TLB:39:40:44:37.38.43,THB:41:40:37:44.42.43,41:42:37:45.40.39,39:38:44:45.40.41| |
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| Structure | 
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