| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Phospholipase A2, major isoenzyme |
|---|
| Ligand | BDBM50280987 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_156338 |
|---|
| IC50 | 5400±n/a nM |
|---|
| Citation |  Wilkerson, WW; Galbraith, W; DeLucca, I; Harris, RR Topical antiinflammatory dehydroabietylamine derivatives. IV Bioorg Med Chem Lett3:2087-2092 (1993) Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Phospholipase A2, major isoenzyme |
|---|
| Name: | Phospholipase A2, major isoenzyme |
|---|
| Synonyms: | Group IB phospholipase A2 | PA21B_PIG | PLA2G1B | Phosphatidylcholine 2-acylhydrolase | Phospholipase A2 |
|---|
| Type: | Hydrolase; monomer or homodimer |
|---|
| Mol. Mass.: | 16279.83 |
|---|
| Organism: | Sus scrofa (pig) |
|---|
| Description: | Purchased from Sigma. |
|---|
| Residue: | 146 |
|---|
| Sequence: | MKFLVLAVLLTVGAAQEGISSRALWQFRSMIKCAIPGSHPLMDFNNYGCYCGLGGSGTPV
DELDRCCETHDNCYRDAKNLDSCKFLVDNPYTESYSYSCSNTEITCNSKNNACEAFICNC
DRNAAICFSKAPYNKEHKNLDTKKYC
|
|
|
|---|
| BDBM50280987 |
|---|
| n/a |
|---|
| Name | BDBM50280987 |
|---|
| Synonyms: | 1N-[12-isopropyl-2,6-dimethyltricyclo[8.4.0.02,7]tetradeca-1(14),10,12-trien-6-ylmethyl]-1,4-pentanediamine | CHEMBL545218 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C25H42N2 |
|---|
| Mol. Mass. | 370.6144 |
|---|
| SMILES | CC(N)CCCNC[C@]1(C)CCC[C@@]2(C)C1CCc1cc(ccc21)C(C)C |r| |
|---|
| Structure | 
|
|---|
Search and Browse
