| Reaction Details |
|---|
 | Report a problem with these data |
| Target | D(1A) dopamine receptor |
|---|
| Ligand | BDBM50281606 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_58323 |
|---|
| IC50 | >6000±n/a nM |
|---|
| Citation |  Jaen, JC; Caprathe, BW; Wise, LD; Meltzer, LT; Pugsley, TA; Huffner, TG Synthesis and pharmacological evaluation of the enantiomers of the dopamine autoreceptor agonist PD 135385 Bioorg Med Chem Lett3:639-644 (1993) Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| D(1A) dopamine receptor |
|---|
| Name: | D(1A) dopamine receptor |
|---|
| Synonyms: | DOPAMINE D1 | DRD1_RAT | Dopamine D1 high | Dopamine D1 low | Dopamine receptor | Dopamine receptor D1 | Dopamine1-like | Drd1 | Drd1a |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 49429.75 |
|---|
| Organism: | RAT |
|---|
| Description: | P18901 |
|---|
| Residue: | 446 |
|---|
| Sequence: | MAPNTSTMDEAGLPAERDFSFRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNF
FVISLAVSDLLVAVLVMPWKAVAEIAGFWPLGPFCNIWVAFDIMCSTASILNLCVISVDR
YWAISSPFQYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTWPLDGNFTSLED
TEDDNCDTRLSRTYAISSSLISFYIPVAIMIVTYTSIYRIAQKQIRRISALERAAVHAKN
CQTTAGNGNPVECAQSESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFISNCMVPFCGS
EETQPFCIDSITFDVFVWFGWANSSLNPIIYAFNADFQKAFSTLLGCYRLCPTTNNAIET
VSINNNGAVVFSSHHEPRGSISKDCNLVYLIPHAVGSSEDLKKEEAGGIAKPLEKLSPAL
SVILDYDTDVSLEKIQPVTHSGQHST
|
|
|
|---|
| BDBM50281606 |
|---|
| n/a |
|---|
| Name | BDBM50281606 |
|---|
| Synonyms: | 1-[2-((R)-4-Phenyl-cyclohex-3-enyl)-ethyl]-4-pyridin-2-yl-piperazine | CHEMBL348547 | PD-137821 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C23H29N3 |
|---|
| Mol. Mass. | 347.4965 |
|---|
| SMILES | C(CN1CCN(CC1)c1ccccn1)[C@@H]1CCC(=CC1)c1ccccc1 |c:19| |
|---|
| Structure | 
|
|---|
Search and Browse
