| Reaction Details |
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 | Report a problem with these data |
| Target | Amine oxidase [flavin-containing] B |
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| Ligand | BDBM50282502 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_123929 (CHEMBL729463) |
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| IC50 | 0.4±n/a nM |
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| Citation |  Rendenbach-Muller, B; Schlecker, R; Traut, M; Weifenbach, H Synthesis of coumarins as subtype-selective inhibitors of monoamine oxidase Bioorg Med Chem Lett4:1195-1198 (1994) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Amine oxidase [flavin-containing] B |
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| Name: | Amine oxidase [flavin-containing] B |
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| Synonyms: | AOFB_RAT | Amine oxidase (flavin-containing) B | Amine oxidase [flavin-containing] B | Maob | Monoamine Oxidase Type B (MAO-B) | Monoamine oxidase | Monoamine oxidase B (MAO-B) | Monoamine oxidase B (rMAO-B) | Monoamine oxidase type B (MAOB) | Monoamine oxidase-B (MAO-B) |
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| Type: | Enzyme |
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| Mol. Mass.: | 58469.65 |
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| Organism: | Rattus norvegicus (rat) |
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| Description: | P19643 |
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| Residue: | 520 |
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| Sequence: | MSNKCDVIVVGGGISGMAAAKLLHDCGLSVVVLEARDRVGGRTYTIRNKNVKYVDLGGSY
VGPTQNRILRLAKELGLETYKVNEVERLIHFVKGKSYAFRGPFPPVWNPITYLDYNNLWR
TMDEMGQEIPSDAPWKAPLAEEWDYMTMKELLDKICWTNSTKQIATLFVNLCVTAETHEV
SALWFLWYVKQCGGTTRIISTTNGGQERKFIGGSGQVSERIKDILGDRVKLERPVIHIDQ
TGENVVVKTLNHEIYEAKYVISAIPPVLGMKIHHSPPLPILRNQLITRVPLGSVIKCMVY
YKEPFWRKKDFCGTMVIEGEEAPIAYTLDDTKPDGSCAAIMGFILAHKARKLVRLTKEER
LRKLCELYAKVLNSQEALQPVHYEEKNWCEEQYSGGCYTAYFPPGILTQYGRVLRQPVGK
IFFAGTETASHWSGYMEGAVEAGERAAREILHAIGKIPEDEIWQPEPESVDVPARPITNT
FLERHLPSVPGLLKLLGLTTILSATALGFLAHKKGLFVRF
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| BDBM50282502 |
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| n/a |
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| Name | BDBM50282502 |
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| Synonyms: | 7-(4-Fluoro-benzyloxy)-3,4-dimethyl-chromen-2-one | 7-(4-fluorobenzyloxy)-3,4-dimethyl-2H-chromen-2-one | CHEMBL276076 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H15FO3 |
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| Mol. Mass. | 298.3083 |
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| SMILES | Cc1c(C)c(=O)oc2cc(OCc3ccc(F)cc3)ccc12 |
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| Structure | 
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