| Reaction Details |
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 | Report a problem with these data |
| Target | Progesterone receptor |
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| Ligand | BDBM50366381 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_159714 |
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| IC50 | 4.5±n/a nM |
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| Citation |  Zhong-Qi, Wang; Shou-Fu, Lu; Lin, Chao; Chuan-Jun, Yang An efficient synthesis and biological activities of 19-nor-17-hydroxy-17-trifluoromethyl-4-estren-3-one and its analogs Bioorg Med Chem Lett5:1899-1902 (1995) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Progesterone receptor |
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| Name: | Progesterone receptor |
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| Synonyms: | Nr3c3 | Nuclear receptor subfamily 3 group C member 3 | PR | PRGR_RAT | Pgr | Progesterone Receptor (PR) | Progesterone receptor |
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| Type: | PROTEIN |
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| Mol. Mass.: | 99414.34 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_159714 |
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| Residue: | 923 |
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| Sequence: | MTELQAKDPRTLHTSGAAPSPTHVGSPLLARLDPDPFQGSQHSDASSVVSPIPISLDRLL
FSRSCQAQELPDEKTQNQQSLSDVEGAFSGVEASRRRSRNPRAPEKDSRLLDSVLDTLLA
PSGPEQSQTSPPACEAITSWCLFGPELPEDPRSVPATKGLLSPLMSRPESKAGDSSGTGA
GQKVLPKAVSPPRQLLLPTSGSAHWPGAGVKPSQQPATVEVEEDGGLETEGSAGPLLKSK
PRALEGMCSGGGVTANAPGAAPGGVTLVPKEDSRFSAPRVSLEQDAPVAPGRSPLATTVV
DFIHVPILPLNHALLAARTRQLLEGDSYDGGAAAQVPFAPPRGSPSAPSPPVPCGDFPDC
TYPPEGDPKEDGFPVYGEFQPPGLKIKEEEEGTEAASRSPRPYLLAGASAATFPDFPLPP
RPPRAPPSRPGEAAVAAPSAAVSPVSSSGSALECILYKAEGAPPTQGSFAPLPCKPPAAS
SCLLPRDSLPAAPTSSAAPAIYPPLGLNGLPQLGYQAAVLKDSLPQVYPPYLNYLRPDSE
ASQSPQYGFDSLPQKICLICGDEASGCHYGVLTCGSCKVFFKRAMEGQHNYLCAGRNDCI
VDKIRRKNCPACRLRKCCQAGMVLGGRKFKKFNKVRVMRALDGVALPQSVAFPNESQTLG
QRITFSPNQEIQLVPPLINLLMSIEPDVVYAGHDNTKPDTSSSLLTSLNQLGERQLLSVV
KWSKSLPGFRNLHIDDQITLIQYSWMSLMVFGLGWRSYKHVSGQMLYFAPDLILNEQRMK
ELSFYSLCLTMWQIPQEFVKLQVTHEEFLCMKVLLLLNTIPLEGLRSQSQFEEMRSSYIR
ELIKAIGLRQKGVVPSSQRFYQLTKLLDSLHDLVKQLHLYCLNTFIQSRALAVEFPEMMS
EVIAAQLPKILAGMVKPLLFHKK
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| BDBM50366381 |
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| n/a |
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| Name | BDBM50366381 |
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| Synonyms: | CHEMBL301446 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H23F3O2 |
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| Mol. Mass. | 340.3799 |
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| SMILES | C[C@]12CCC3=C4CCC(=O)C=C4CCC3C1CC[C@@]2(O)C(F)(F)F |c:4,10| |
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| Structure | 
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