| Reaction Details |
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 | Report a problem with these data |
| Target | B2 bradykinin receptor |
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| Ligand | BDBM50289767 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_40427 |
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| Ki | 4950±n/a nM |
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| Citation |  Salvino, JM; Seoane, PR; Douty, BD; Awad, MA; Hoyer, D; Ross, TM; Dolle, RE; Houck, WT; Faunce, DM; Sawutz, DG Structure activity relationships of non-peptide bradykinin B2 receptor antagonists Bioorg Med Chem Lett5:357-362 (1995) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| B2 bradykinin receptor |
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| Name: | B2 bradykinin receptor |
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| Synonyms: | B2 BRADYKININ | B2 bradykinin receptor | B2R | BDKRB2 | BK-2 receptor | BKR2 | BKRB2_HUMAN | Bradykinin B2 receptor |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 44467.17 |
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| Organism: | Homo sapiens (Human) |
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| Description: | B2 BRADYKININ BDKRB2 HUMAN::P30411 |
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| Residue: | 391 |
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| Sequence: | MFSPWKISMFLSVREDSVPTTASFSADMLNVTLQGPTLNGTFAQSKCPQVEWLGWLNTIQ
PPFLWVLFVLATLENIFVLSVFCLHKSSCTVAEIYLGNLAAADLILACGLPFWAITISNN
FDWLFGETLCRVVNAIISMNLYSSICFLMLVSIDRYLALVKTMSMGRMRGVRWAKLYSLV
IWGCTLLLSSPMLVFRTMKEYSDEGHNVTACVISYPSLIWEVFTNMLLNVVGFLLPLSVI
TFCTMQIMQVLRNNEMQKFKEIQTERRATVLVLVVLLLFIICWLPFQISTFLDTLHRLGI
LSSCQDERIIDVITQIASFMAYSNSCLNPLVYVIVGKRFRKKSWEVYQGVCQKGGCRSEP
IQMENSMGTLRTSISVERQIHKLQDWAGSRQ
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| BDBM50289767 |
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| n/a |
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| Name | BDBM50289767 |
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| Synonyms: | (S)-2-(N',N''-Dicyclohexyl-guanidino)-N-(4-hydroxymethyl-phenyl)-3-naphthalen-2-yl-propionamide | 2-(N',N''-Dicyclohexyl-guanidino)-N-(4-hydroxymethyl-phenyl)-3-naphthalen-2-yl-propionamide | CHEMBL298832 |
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| Type | Small organic molecule |
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| Emp. Form. | C33H42N4O2 |
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| Mol. Mass. | 526.7122 |
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| SMILES | [#8]-[#6]-c1ccc(-[#7]-[#6](=O)-[#6@H](-[#6]-c2ccc3ccccc3c2)\[#7]=[#6](/[#7]-[#6]-2-[#6]-[#6]-[#6]-[#6]-[#6]-2)-[#7]-[#6]-2-[#6]-[#6]-[#6]-[#6]-[#6]-2)cc1 |
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| Structure | 
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