| Reaction Details |
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 | Report a problem with these data |
| Target | Amine oxidase [flavin-containing] B |
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| Ligand | BDBM50287897 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_123928 |
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| IC50 | 400±n/a nM |
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| Citation |  Arvanitis, AG; Scholfield, EL; Grigoriadis, D; Heytler, PG; Bowdle, J; Chorvat, RJ Alkylbenzyl ethers of hydroquinones as monoamine oxidase B inhibitors Bioorg Med Chem Lett6:115-120 (1996) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Amine oxidase [flavin-containing] B |
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| Name: | Amine oxidase [flavin-containing] B |
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| Synonyms: | AOFB_RAT | Amine oxidase (flavin-containing) B | Amine oxidase [flavin-containing] B | Maob | Monoamine Oxidase Type B (MAO-B) | Monoamine oxidase | Monoamine oxidase B (MAO-B) | Monoamine oxidase B (rMAO-B) | Monoamine oxidase type B (MAOB) | Monoamine oxidase-B (MAO-B) |
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| Type: | Enzyme |
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| Mol. Mass.: | 58469.65 |
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| Organism: | Rattus norvegicus (rat) |
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| Description: | P19643 |
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| Residue: | 520 |
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| Sequence: | MSNKCDVIVVGGGISGMAAAKLLHDCGLSVVVLEARDRVGGRTYTIRNKNVKYVDLGGSY
VGPTQNRILRLAKELGLETYKVNEVERLIHFVKGKSYAFRGPFPPVWNPITYLDYNNLWR
TMDEMGQEIPSDAPWKAPLAEEWDYMTMKELLDKICWTNSTKQIATLFVNLCVTAETHEV
SALWFLWYVKQCGGTTRIISTTNGGQERKFIGGSGQVSERIKDILGDRVKLERPVIHIDQ
TGENVVVKTLNHEIYEAKYVISAIPPVLGMKIHHSPPLPILRNQLITRVPLGSVIKCMVY
YKEPFWRKKDFCGTMVIEGEEAPIAYTLDDTKPDGSCAAIMGFILAHKARKLVRLTKEER
LRKLCELYAKVLNSQEALQPVHYEEKNWCEEQYSGGCYTAYFPPGILTQYGRVLRQPVGK
IFFAGTETASHWSGYMEGAVEAGERAAREILHAIGKIPEDEIWQPEPESVDVPARPITNT
FLERHLPSVPGLLKLLGLTTILSATALGFLAHKKGLFVRF
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| BDBM50287897 |
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| n/a |
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| Name | BDBM50287897 |
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| Synonyms: | 4-[2-Acetyl-4-(3,4-dimethyl-benzyloxy)-phenoxy]-butyronitrile | CHEMBL18954 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H23NO3 |
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| Mol. Mass. | 337.4122 |
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| SMILES | CC(=O)c1cc(OCc2ccc(C)c(C)c2)ccc1OCCCC#N |
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| Structure | 
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