| Reaction Details |
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 | Report a problem with these data |
| Target | Kynureninase |
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| Ligand | BDBM50288257 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_91720 |
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| Ki | 8800±n/a nM |
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| Citation |  Ross, FC; Botting, NP; Leeson, PD Synthesis of phosphinic acid transition state analogues for the reaction catalysed by kynureninase Bioorg Med Chem Lett6:2643-2646 (1996) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Kynureninase |
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| Name: | Kynureninase |
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| Synonyms: | KYNU | KYNU_HUMAN | L-kynurenine hydrolase |
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| Type: | PROTEIN |
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| Mol. Mass.: | 52356.52 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_91729 |
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| Residue: | 465 |
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| Sequence: | MEPSSLELPADTVQRIAAELKCHPTDERVALHLDEEDKLRHFRECFYIPKIQDLPPVDLS
LVNKDENAIYFLGNSLGLQPKMVKTYLEEELDKWAKIAAYGHEVGKRPWITGDESIVGLM
KDIVGANEKEIALMNALTVNLHLLMLSFFKPTPKRYKILLEAKAFPSDHYAIESQLQLHG
LNIEESMRMIKPREGEETLRIEDILEVIEKEGDSIAVILFSGVHFYTGQHFNIPAITKAG
QAKGCYVGFDLAHAVGNVELYLHDWGVDFACWCSYKYLNAGAGGIAGAFIHEKHAHTIKP
ALVGWFGHELSTRFKMDNKLQLIPGVCGFRISNPPILLVCSLHASLEIFKQATMKALRKK
SVLLTGYLEYLIKHNYGKDKAATKKPVVNIITPSHVEERGCQLTITFSVPNKDVFQELEK
RGVVCDKRNPNGIRVAPVPLYNSFHDVYKFTNLLTSILDSAETKN
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| BDBM50288257 |
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| n/a |
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| Name | BDBM50288257 |
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| Synonyms: | (R)-2-Benzyloxycarbonylamino-3-(methoxy-phenyl-phosphinoyl)-propionic acid methyl ester | CHEMBL89851 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H22NO6P |
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| Mol. Mass. | 391.3548 |
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| SMILES | COC(=O)[C@H](CP(=O)(OC)c1ccccc1)NC(=O)OCc1ccccc1 |
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| Structure | 
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