Reaction Details | |||
---|---|---|---|
Report a problem with these data | |||
Target | 5-hydroxytryptamine receptor 4 | ||
Ligand | BDBM50288586 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | ChEMBL_3344 (CHEMBL619044) | ||
Ki | 115±n/a nM | ||
Citation | Fancelli, D; Caccia, C; Fornaretto, M; McArthur, R; Severino, D; Vaghi, F; Varasi, M Serotoninergic 5-HT3 and 5-HT4 receptor activities of dihydrobenzofuran carboxylic acid derivatives Bioorg Med Chem Lett6:263-266 (1996) Article | ||
More Info.: | Get all data from this article, Assay Method | ||
5-hydroxytryptamine receptor 4 | |||
Name: | 5-hydroxytryptamine receptor 4 | ||
Synonyms: | 5-HT-4 | 5-HT4 | 5-HT4L | 5-HT4S | 5-hydroxytryptamine receptor 4 | 5HT4R_RAT | Htr4 | Serotonin (5-HT) receptor | Serotonin 4 (5-HT4) receptor | ||
Type: | Enzyme Catalytic Domain | ||
Mol. Mass.: | 46117.31 | ||
Organism: | RAT | ||
Description: | 5-HT4 HTR4 RAT::Q62758 | ||
Residue: | 406 | ||
Sequence: |
| ||
BDBM50288586 | |||
n/a | |||
Name | BDBM50288586 | ||
Synonyms: | 2-(4-amino-5-chloro-2,3-dihydrobenzo[b]furan-7-ylcarboxamido)-(2R)-4-azabicyclo[2.2.2]octane | CHEMBL89259 | ||
Type | Small organic molecule | ||
Emp. Form. | C16H20ClN3O2 | ||
Mol. Mass. | 321.802 | ||
SMILES | Nc1c2CCOc2c(cc1Cl)C(=O)N[C@H]1CN2CCC1CC2 |wD:14.15,(8.91,-10.5,;8.98,-8.96,;10.32,-8.27,;11.76,-8.8,;12.71,-7.59,;11.85,-6.32,;10.38,-6.73,;9.09,-5.92,;7.73,-6.61,;7.66,-8.16,;6.34,-8.93,;9.16,-4.38,;7.86,-3.56,;10.51,-3.65,;10.57,-2.13,;11.94,-1.42,;12.01,.11,;10.73,-.78,;10.09,-.14,;9.27,-1.32,;9.32,.22,;10.7,.95,)| | ||
Structure |