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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | 5-hydroxytryptamine receptor 4 | ||
| Ligand | BDBM50288589 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_3326 (CHEMBL619026) | ||
| EC50 | 385±n/a nM | ||
| Citation |  Fancelli, D; Caccia, C; Fornaretto, M; McArthur, R; Severino, D; Vaghi, F; Varasi, M Serotoninergic 5-HT3 and 5-HT4 receptor activities of dihydrobenzofuran carboxylic acid derivatives Bioorg Med Chem Lett6:263-266 (1996) Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| 5-hydroxytryptamine receptor 4 | |||
| Name: | 5-hydroxytryptamine receptor 4 | ||
| Synonyms: | 5-HT-4 | 5-HT4 | 5-HT4L | 5-HT4S | 5-hydroxytryptamine receptor 4 | 5HT4R_RAT | Htr4 | Serotonin (5-HT) receptor | Serotonin 4 (5-HT4) receptor | ||
| Type: | Enzyme Catalytic Domain | ||
| Mol. Mass.: | 46117.31 | ||
| Organism: | RAT | ||
| Description: | 5-HT4 HTR4 RAT::Q62758 | ||
| Residue: | 406 | ||
| Sequence: |
| ||
| BDBM50288589 | |||
| n/a | |||
| Name | BDBM50288589 | ||
| Synonyms: | 4-Amino-5-chloro-2,3-dihydro-benzofuran-7-carboxylic acid (R)-(1-aza-bicyclo[2.2.2]oct-3-yl) ester | CHEMBL315443 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C16H19ClN2O3 | ||
| Mol. Mass. | 322.787 | ||
| SMILES | Nc1c2CCOc2c(cc1Cl)C(=O)O[C@H]1CN2CCC1CC2 |wD:14.15,(8.96,-10.53,;9.01,-8.99,;10.36,-8.28,;11.81,-8.8,;12.77,-7.61,;11.91,-6.31,;10.42,-6.74,;9.12,-5.92,;7.77,-6.61,;7.71,-8.19,;6.36,-8.93,;9.19,-4.37,;7.89,-3.56,;10.55,-3.66,;10.6,-2.11,;11.98,-1.42,;12.05,.13,;10.76,-.78,;10.12,-.14,;9.3,-1.31,;9.37,.24,;10.74,.95,)| | ||
| Structure | 
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