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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Prothrombin | ||
| Ligand | BDBM50069193 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEBML_208316 | ||
| Ki | 47±n/a nM | ||
| Citation |  Sanderson, PE; Dyer, DL; Naylor-Olsen, AM; Vacca, JP; Gardell, SJ; Dale Lewis, S; Lucas, BJ; Lyle, EA; Lynch, JJ; Mulichak, AM L-373,890, An achiral, noncovalent, subnanomolar thrombin inhibitor Bioorg Med Chem Lett7:1497-1500 (1997) Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Prothrombin | |||
| Name: | Prothrombin | ||
| Synonyms: | Activation peptide fragment 1 | Activation peptide fragment 2 | Coagulation factor II | F2 | Prothrombin precursor | THRB_HUMAN | Thrombin heavy chain | Thrombin light chain | ||
| Type: | Protein | ||
| Mol. Mass.: | 70029.57 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P00734 | ||
| Residue: | 622 | ||
| Sequence: |
| ||
| BDBM50069193 | |||
| n/a | |||
| Name | BDBM50069193 | ||
| Synonyms: | CHEMBL424545 | N-(4-Amino-cyclohexylmethyl)-2-(6-methyl-2-oxo-3-phenethylamino-2H-pyridin-1-yl)-acetamide | ||
| Type | Small organic molecule | ||
| Emp. Form. | C23H32N4O2 | ||
| Mol. Mass. | 396.5258 | ||
| SMILES | Cc1ccc(NCCc2ccccc2)c(=O)n1CC(=O)NC[C@H]1CC[C@H](N)CC1 |wU:22.23,wD:25.27,(10.88,-.69,;9.55,-1.46,;8.19,-.69,;6.86,-1.46,;6.86,-3,;5.53,-3.77,;4.19,-3,;4.19,-1.46,;2.86,-.71,;1.55,-1.48,;.22,-.73,;.19,.8,;1.5,1.58,;2.84,.83,;8.19,-3.77,;8.21,-5.32,;9.55,-3,;10.88,-3.77,;10.88,-5.32,;12.21,-6.09,;9.55,-6.09,;9.55,-7.63,;10.88,-8.4,;12.21,-7.63,;13.55,-8.4,;13.55,-9.95,;14.88,-10.72,;12.21,-10.72,;10.88,-9.95,)| | ||
| Structure | 
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