| Reaction Details |
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 | Report a problem with these data |
| Target | Serine protease 1 |
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| Ligand | BDBM50289526 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_212727 |
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| Ki | 890±n/a nM |
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| Citation |  Sanderson, PE; Dyer, DL; Naylor-Olsen, AM; Vacca, JP; Gardell, SJ; Dale Lewis, S; Lucas, BJ; Lyle, EA; Lynch, JJ; Mulichak, AM L-373,890, An achiral, noncovalent, subnanomolar thrombin inhibitor Bioorg Med Chem Lett7:1497-1500 (1997) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Serine protease 1 |
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| Name: | Serine protease 1 |
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| Synonyms: | Alpha-trypsin chain 1 | Alpha-trypsin chain 2 | Beta-trypsin | Cationic trypsinogen | PRSS1 | Serine protease 1 | TRP1 | TRY1 | TRY1_HUMAN | TRYP1 | Thrombin & trypsin | Trypsin | Trypsin I | Trypsin-1 |
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| Type: | Enzyme |
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| Mol. Mass.: | 26557.80 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P07477 |
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| Residue: | 247 |
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| Sequence: | MNPLLILTFVAAALAAPFDDDDKIVGGYNCEENSVPYQVSLNSGYHFCGGSLINEQWVVS
AGHCYKSRIQVRLGEHNIEVLEGNEQFINAAKIIRHPQYDRKTLNNDIMLIKLSSRAVIN
ARVSTISLPTAPPATGTKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKIT
SNMFCVGFLEGGKDSCQGDSGGPVVCNGQLQGVVSWGDGCAQKNKPGVYTKVYNYVKWIK
NTIAANS
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| BDBM50289526 |
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| n/a |
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| Name | BDBM50289526 |
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| Synonyms: | CHEMBL37035 | N-(1-{[(1-Carbamimidoyl-piperidin-4-ylmethyl)-carbamoyl]-methyl}-6-methyl-2-oxo-1,2-dihydro-pyridin-3-yl)-3,3-diphenyl-propionamide |
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| Type | Small organic molecule |
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| Emp. Form. | C30H36N6O3 |
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| Mol. Mass. | 528.6452 |
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| SMILES | Cc1ccc(NC(=O)CC(c2ccccc2)c2ccccc2)c(=O)n1CC(=O)NCC1CCN(CC1)C(N)=N |
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| Structure | 
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