Reaction Details | |||
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Target | D(2) dopamine receptor | ||
Ligand | BDBM50290224 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | ChEBML_58455 | ||
Ki | 12±n/a nM | ||
Citation | Belliotti, TR; Kesten, SR; Rubin, JR; Wustrow, DJ; Georgic, LM; Zoski, KT; Akunne, HC; Wise, LD Novel cyclohexyl amides as potent and selective D3 dopamine receptor ligands Bioorg Med Chem Lett7:2403-2408 (1997) Article | ||
More Info.: | Get all data from this article, Assay Method | ||
D(2) dopamine receptor | |||
Name: | D(2) dopamine receptor | ||
Synonyms: | D(2) dopamine receptor | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2 | DRD2_HUMAN | Dopamine D2 receptor | Dopamine D2 receptor (D2) | Dopamine D2 receptor (D2R) | Dopamine D2A | Dopamine2-like | d2 | ||
Type: | Cell-surface receptors | ||
Mol. Mass.: | 50647.10 | ||
Organism: | Homo sapiens (Human) | ||
Description: | P14416 | ||
Residue: | 443 | ||
Sequence: |
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BDBM50290224 | |||
n/a | |||
Name | BDBM50290224 | ||
Synonyms: | CHEMBL78195 | Cycloheptanecarboxylic acid (4-{2-[4-(2,3-dichloro-phenyl)-piperazin-1-yl]-ethyl}-cyclohexyl)-amide | ||
Type | Small organic molecule | ||
Emp. Form. | C26H39Cl2N3O | ||
Mol. Mass. | 480.513 | ||
SMILES | Clc1cccc(N2CCN(CC[C@H]3CC[C@@H](CC3)NC(=O)C3CCCCCC3)CC2)c1Cl |wU:12.11,wD:15.18,(20.58,-4.52,;19.85,-5.88,;20.65,-7.21,;19.91,-8.57,;18.36,-8.59,;17.57,-7.27,;16.02,-7.3,;15.24,-5.99,;13.7,-6.02,;12.95,-7.37,;11.41,-7.4,;10.64,-8.73,;9.1,-8.74,;8.32,-10.08,;6.78,-10.09,;6.01,-8.75,;6.77,-7.42,;8.31,-7.41,;4.45,-8.75,;3.7,-10.09,;2.16,-10.1,;4.57,-11.34,;3.26,-11.95,;3,-13.29,;3.84,-14.17,;5.25,-14.17,;6.08,-13.34,;5.85,-11.99,;13.76,-8.67,;15.3,-8.64,;18.32,-5.92,;17.51,-4.61,)| | ||
Structure |