| Reaction Details |
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 | Report a problem with these data |
| Target | D(4) dopamine receptor |
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| Ligand | BDBM50071215 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_63086 (CHEMBL676182) |
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| IC50 | 2.00±n/a nM |
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| Citation |  Arlt, M; Böttcher, H; Riethmüller, A; Schneider, G; Bartoszyk, GD; Greiner, H; Seyfried, CA SAR of novel biarylmethylamine dopamine D4 receptor ligands. Bioorg Med Chem Lett8:2033-8 (1999) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| D(4) dopamine receptor |
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| Name: | D(4) dopamine receptor |
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| Synonyms: | D(2C) dopamine receptor | DOPAMINE D4 | DOPAMINE D4.2 | DOPAMINE D4.4 | DRD4 | DRD4_HUMAN | Dopamine D4 receptor |
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| Type: | Enzyme |
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| Mol. Mass.: | 48373.19 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P21917 |
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| Residue: | 419 |
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| Sequence: | MGNRSTADADGLLAGRGPAAGASAGASAGLAGQGAAALVGGVLLIGAVLAGNSLVCVSVA
TERALQTPTNSFIVSLAAADLLLALLVLPLFVYSEVQGGAWLLSPRLCDALMAMDVMLCT
ASIFNLCAISVDRFVAVAVPLRYNRQGGSRRQLLLIGATWLLSAAVAAPVLCGLNDVRGR
DPAVCRLEDRDYVVYSSVCSFFLPCPLMLLLYWATFRGLQRWEVARRAKLHGRAPRRPSG
PGPPSPTPPAPRLPQDPCGPDCAPPAPGLPRGPCGPDCAPAAPSLPQDPCGPDCAPPAPG
LPPDPCGSNCAPPDAVRAAALPPQTPPQTRRRRRAKITGRERKAMRVLPVVVGAFLLCWT
PFFVVHITQALCPACSVPPRLVSAVTWLGYVNSALNPVIYTVFNAEFRNVFRKALRACC
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| BDBM50071215 |
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| n/a |
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| Name | BDBM50071215 |
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| Synonyms: | 2-[4-(4'-Fluoro-biphenyl-3-ylmethyl)-piperazin-1-yl]-pyrimidine | CHEMBL59942 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H21FN4 |
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| Mol. Mass. | 348.4166 |
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| SMILES | Fc1ccc(cc1)-c1cccc(CN2CCN(CC2)c2ncccn2)c1 |
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| Structure | 
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