| Reaction Details |
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 | Report a problem with these data |
| Target | Lysosomal alpha-glucosidase |
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| Ligand | BDBM50070029 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_34406 |
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| Ki | 75000±n/a nM |
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| Citation |  Therisod, H; Letourneux, Y; Therisod, M A new strong inhibitor of beta-mannosidase. Bioorg Med Chem Lett8:371-2 (1999) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Lysosomal alpha-glucosidase |
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| Name: | Lysosomal alpha-glucosidase |
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| Synonyms: | 70 kDa lysosomal alpha-glucosidase | 76 kDa lysosomal alpha-glucosidase | Acid maltase | Aglucosidase alfa | Alpha glucosidase | GAA | LYAG_HUMAN |
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| Type: | PROTEIN |
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| Mol. Mass.: | 105312.45 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1506060 |
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| Residue: | 952 |
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| Sequence: | MGVRHPPCSHRLLAVCALVSLATAALLGHILLHDFLLVPRELSGSSPVLEETHPAHQQGA
SRPGPRDAQAHPGRPRAVPTQCDVPPNSRFDCAPDKAITQEQCEARGCCYIPAKQGLQGA
QMGQPWCFFPPSYPSYKLENLSSSEMGYTATLTRTTPTFFPKDILTLRLDVMMETENRLH
FTIKDPANRRYEVPLETPHVHSRAPSPLYSVEFSEEPFGVIVRRQLDGRVLLNTTVAPLF
FADQFLQLSTSLPSQYITGLAEHLSPLMLSTSWTRITLWNRDLAPTPGANLYGSHPFYLA
LEDGGSAHGVFLLNSNAMDVVLQPSPALSWRSTGGILDVYIFLGPEPKSVVQQYLDVVGY
PFMPPYWGLGFHLCRWGYSSTAITRQVVENMTRAHFPLDVQWNDLDYMDSRRDFTFNKDG
FRDFPAMVQELHQGGRRYMMIVDPAISSSGPAGSYRPYDEGLRRGVFITNETGQPLIGKV
WPGSTAFPDFTNPTALAWWEDMVAEFHDQVPFDGMWIDMNEPSNFIRGSEDGCPNNELEN
PPYVPGVVGGTLQAATICASSHQFLSTHYNLHNLYGLTEAIASHRALVKARGTRPFVISR
STFAGHGRYAGHWTGDVWSSWEQLASSVPEILQFNLLGVPLVGADVCGFLGNTSEELCVR
WTQLGAFYPFMRNHNSLLSLPQEPYSFSEPAQQAMRKALTLRYALLPHLYTLFHQAHVAG
ETVARPLFLEFPKDSSTWTVDHQLLWGEALLITPVLQAGKAEVTGYFPLGTWYDLQTVPV
EALGSLPPPPAAPREPAIHSEGQWVTLPAPLDTINVHLRAGYIIPLQGPGLTTTESRQQP
MALAVALTKGGEARGELFWDDGESLEVLERGAYTQVIFLARNNTIVNELVRVTSEGAGLQ
LQKVTVLGVATAPQQVLSNGVPVSNFTYSPDTKVLDICVSLLMGEQFLVSWC
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| BDBM50070029 |
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| n/a |
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| Name | BDBM50070029 |
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| Synonyms: | (2Z)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-one O-(anilinocarbonyl)oxime | CHEMBL62552 |
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| Type | Small organic molecule |
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| Emp. Form. | C13H16N2O7 |
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| Mol. Mass. | 312.2753 |
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| SMILES | OCC1OC(=NOC(=O)Nc2ccccc2)C(O)C(O)C1O |w:5.5| |
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| Structure | 
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