| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Carbonic anhydrase 2 |
|---|
| Ligand | BDBM50079043 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_45239 |
|---|
| Ki | 28±n/a nM |
|---|
| Citation |  Scozzafava, A; Supuran, CT Carbonic anhydrase inhibitors: synthesis of N-morpholylthiocarbonylsulfenylamino aromatic/heterocyclic sulfonamides and their interaction with isozymes I, II and IV. Bioorg Med Chem Lett10:1117-20 (2000) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Carbonic anhydrase 2 |
|---|
| Name: | Carbonic anhydrase 2 |
|---|
| Synonyms: | CA-II | CA2 | CAC | CAH2_HUMAN | Carbonate dehydratase II | Carbonic anhydrase 2 (CA II) | Carbonic anhydrase 2 (CA-II) | Carbonic anhydrase 2 (Recombinant CA II) | Carbonic anhydrase C | Carbonic anhydrase II (CA II) | Carbonic anhydrase II (CA-II) | Carbonic anhydrase II (CAII) | Carbonic anhydrase II (hCA II) | Carbonic anhydrase isoenzyme II (hCA II) |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 29250.71 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P00918 |
|---|
| Residue: | 260 |
|---|
| Sequence: | MSHHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRIL
NNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHL
VHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDP
RGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELM
VDNWRPAQPLKNRQIKASFK
|
|
|
|---|
| BDBM50079043 |
|---|
| n/a |
|---|
| Name | BDBM50079043 |
|---|
| Synonyms: | 4-Amino-5,6-dichloro-benzene-1,3-disulfonic acid diamide | 4-amino-5,6-dichlorobenzene-1,3-disulfonamide | BDBM50222601 | CHEMBL269628 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C6H7Cl2N3O4S2 |
|---|
| Mol. Mass. | 320.173 |
|---|
| SMILES | Nc1c(Cl)c(Cl)c(cc1S(N)(=O)=O)S(N)(=O)=O |
|---|
| Structure | 
|
|---|
Search and Browse
