| Reaction Details |
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 | Report a problem with these data |
| Target | Glutamate receptor ionotropic, kainate 2 |
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| Ligand | BDBM50089912 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_71992 |
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| Ki | 450±n/a nM |
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| Citation |  Baker, SR; Bleakman, D; Ezquerra, J; Ballyk, BA; Deverill, M; Ho, K; Kamboj, RK; Collado, I; Domínguez, C; Escribano, A; Mateo, AI; Pedregal, C; Rubio, A 4-Alkylidenyl glutamic acids, potent and selective GluR5 agonists. Bioorg Med Chem Lett10:1807-10 (2000) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Glutamate receptor ionotropic, kainate 2 |
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| Name: | Glutamate receptor ionotropic, kainate 2 |
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| Synonyms: | EAA4 | Excitatory amino acid receptor 4 | GLUR6 | GRIK2 | GRIK2_HUMAN | GluK2 | GluR-6 | Glutamate kainate | Glutamate receptor 6 | Glutamate receptor ionotropic kainate 2 | Glutamate receptor, ionotropic kainate 2 | Glutamate-Kainate | Glutamate-Kainate, GluR6 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 102592.78 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q13002 |
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| Residue: | 908 |
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| Sequence: | MKIIFPILSNPVFRRTVKLLLCLLWIGYSQGTTHVLRFGGIFEYVESGPMGAEELAFRFA
VNTINRNRTLLPNTTLTYDTQKINLYDSFEASKKACDQLSLGVAAIFGPSHSSSANAVQS
ICNALGVPHIQTRWKHQVSDNKDSFYVSLYPDFSSLSRAILDLVQFFKWKTVTVVYDDST
GLIRLQELIKAPSRYNLRLKIRQLPADTKDAKPLLKEMKRGKEFHVIFDCSHEMAAGILK
QALAMGMMTEYYHYIFTTLDLFALDVEPYRYSGVNMTGFRILNTENTQVSSIIEKWSMER
LQAPPKPDSGLLDGFMTTDAALMYDAVHVVSVAVQQFPQMTVSSLQCNRHKPWRFGTRFM
SLIKEAHWEGLTGRITFNKTNGLRTDFDLDVISLKEEGLEKIGTWDPASGLNMTESQKGK
PANITDSLSNRSLIVTTILEEPYVLFKKSDKPLYGNDRFEGYCIDLLRELSTILGFTYEI
RLVEDGKYGAQDDANGQWNGMVRELIDHKADLAVAPLAITYVREKVIDFSKPFMTLGISI
LYRKPNGTNPGVFSFLNPLSPDIWMYILLAYLGVSCVLFVIARFSPYEWYNPHPCNPDSD
VVENNFTLLNSFWFGVGALMQQGSELMPKALSTRIVGGIWWFFTLIIISSYTANLAAFLT
VERMESPIDSADDLAKQTKIEYGAVEDGATMTFFKKSKISTYDKMWAFMSSRRQSVLVKS
NEEGIQRVLTSDYAFLMESTTIEFVTQRNCNLTQIGGLIDSKGYGVGTPMGSPYRDKITI
AILQLQEEGKLHMMKEKWWRGNGCPEEESKEASALGVQNIGGIFIVLAAGLVLSVFVAVG
EFLYKSKKNAQLEKRSFCSAMVEELRMSLKCQRRLKHKPQAPVIVKTEEVINMHTFNDRR
LPGKETMA
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| BDBM50089912 |
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| n/a |
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| Name | BDBM50089912 |
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| Synonyms: | (2S)-2-amino-4-methylidenepentanedioic acid | 4-methylene-L-glutamic acid | CHEMBL38499 |
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| Type | Small organic molecule |
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| Emp. Form. | C6H9NO4 |
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| Mol. Mass. | 159.14 |
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| SMILES | N[C@@H](CC(=C)C(O)=O)C(O)=O |
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| Structure | 
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