| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Kappa-type opioid receptor |
|---|
| Ligand | BDBM50093784 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_145823 |
|---|
| Ki | 1115±n/a nM |
|---|
| Citation |  Coop, A; Jacobson, AE; Aceto, MD; Harris, LS; Traynor, JR; Woods, JH; Rice, KC N-Cyclohexylethyl-N-noroxymorphindole: a mu-opioid preferring analogue of naltrindole. Bioorg Med Chem Lett10:2449-51 (2001) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Kappa-type opioid receptor |
|---|
| Name: | Kappa-type opioid receptor |
|---|
| Synonyms: | KOR-1 | Kappa Opioid Receptor | OPIATE Kappa | OPRK_RAT | Opioid receptor | Oprk1 | Ror-d |
|---|
| Type: | G Protein-Coupled Receptor (GPCR) |
|---|
| Mol. Mass.: | 42692.90 |
|---|
| Organism: | Rattus norvegicus (rat) |
|---|
| Description: | P34975 |
|---|
| Residue: | 380 |
|---|
| Sequence: | MESPIQIFRGEPGPTCAPSACLLPNSSSWFPNWAESDSNGSVGSEDQQLEPAHISPAIPV
IITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSAVYL
MNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINI
CIWLLASSVGISAIVLGGTKVREDVDVIECSLQFPDDEYSWWDLFMKICVFVFAFVIPVL
IIIVCYTLMILRLKSVRLLSGSREKDRNLRRITKLVLVVVAVFIICWTPIHIFILVEALG
STSHSTAVLSSYYFCIALGYTNSSLNPVLYAFLDENFKRCFRDFCFPIKMRMERQSTNRV
RNTVQDPASMRDVGGMNKPV
|
|
|
|---|
| BDBM50093784 |
|---|
| n/a |
|---|
| Name | BDBM50093784 |
|---|
| Synonyms: | CHEMBL79443 | [1,5-3H]-17-Cyclohexylmethyl-6,7-dehydro-4,5a -epoxy-3,14-dihydroxy-6,7-2,3-indolo-morphinan |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C29H32N2O3 |
|---|
| Mol. Mass. | 456.576 |
|---|
| SMILES | Oc1ccc2C[C@H]3N(CC4CCCCC4)CCC45C(Oc1c24)c1[nH]c2ccccc2c1C[C@@]35O |THB:8:7:32:21.4.5| |
|---|
| Structure | 
|
|---|
Search and Browse
