| Reaction Details |
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 | Report a problem with these data |
| Target | Metabotropic glutamate receptor 8 |
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| Ligand | BDBM50100942 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_104623 (CHEMBL715571) |
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| EC50 | 53000±n/a nM |
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| Citation |  Bessis, AS; Bolte, J; Pin, JP; Acher, F New probes of the agonist binding site of metabotropic glutamate receptors. Bioorg Med Chem Lett11:1569-72 (2001) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Metabotropic glutamate receptor 8 |
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| Name: | Metabotropic glutamate receptor 8 |
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| Synonyms: | GRM8_RAT | Gprc1h | Grm8 | Metabotropic glutamate receptor | Metabotropic glutamate receptor 8 (mGlu8) | Mglur8 | glutamate receptor, metabotropic 8 precursor | mGlu8 | metabotropic glutamate 8 |
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| Type: | Enzyme |
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| Mol. Mass.: | 101886.18 |
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| Organism: | Rattus norvegicus (Rat) |
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| Description: | P70579 |
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| Residue: | 908 |
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| Sequence: | MVCEGKRLASCPCFFLLTAKFYWILTMMQRTHSQEYAHSIRVDGDIILGGLFPVHAKGER
GVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFV
QALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTA
PELSDNTRYDFFSRVVPPDSYQAQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISR
EIGGVCIAQSQKIPREPRPGEFEKIIKRLLETPNARAVIMFANEDDIRRILEAAKKLNQS
GHFLWIGSDSWGSKIAPVYQQEEIAEGAVTILPKRASIDGFDRYFRSRTLANNRRNVWFA
EFWEENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMH
KERCPGYIGLCPRMVTIDGKELLGYIRAVNFNGSAGTPVTFNENGDAPGRYDIFQYQINN
KSTEYKIIGHWTNQLHLKVEDMQWANREHTHPASVCSLPCKPGERKKTVKGVPCCWHCER
CEGYNYQVDELSCELCPLDQRPNINRTGCQRIPIIKLEWHSPWAVVPVFIAILGIIATTF
VIVTFVRYNDTPIVRASGRELSYVLLTGIFLCYSITFLMIAAPDTIICSFRRIFLGLGMC
FSYAALLTKTNRIHRIFEQGKKSVTAPKFISPASQLVITFSLISVQLLGVFVWFVVDPPH
TIIDYGEQRTLDPENARGVLKCDISDLSLICSLGYSILLMVTCTVYAIKTRGVPETFNEA
KPIGFTMYTTCIIWLAFIPIFFGTAQSAEKMYIQTTTLTVSMSLSASVSLGMLYMPKVYI
IIFHPEQNVQKRKRSFKAVVTAATMQSKLIQKGNDRPNGEVKSELCESLETNTSSTKTTY
ISYSNHSI
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| BDBM50100942 |
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| n/a |
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| Name | BDBM50100942 |
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| Synonyms: | (2S,4S)-2-ammonio-4-carboxy-4-hydroxybutanoate |
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| Type | Small organic molecule |
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| Emp. Form. | C5H9NO5 |
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| Mol. Mass. | 163.1287 |
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| SMILES | [NH3+][C@@H](C[C@H](O)C(O)=O)C([O-])=O |
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| Structure | 
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