| Reaction Details |
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 | Report a problem with these data |
| Target | Phenylethanolamine N-methyltransferase |
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| Ligand | BDBM50081952 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_152560 |
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| Ki | 380±n/a nM |
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| Citation |  Grunewald, GL; McLeish, MJ; Criscione, KR Phenylethanolamine N-methyltransferase kinetics: bovine versus recombinant human enzyme. Bioorg Med Chem Lett11:1579-82 (2001) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Phenylethanolamine N-methyltransferase |
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| Name: | Phenylethanolamine N-methyltransferase |
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| Synonyms: | Noradrenaline N-methyltransferase | PNMT | PNMT_BOVIN | PNMTase |
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| Type: | Enzyme |
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| Mol. Mass.: | 30916.97 |
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| Organism: | Bos taurus (bovine) |
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| Description: | n/a |
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| Residue: | 283 |
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| Sequence: | MSGTDRSQAAGAVPDSDPGLAAVSSAYQRFEPRAYLRNNYAPPRGDLSCPDGVGPWKLRC
LAQTFATGEVSGRTLIDIGSGPTIYQLLSACAHFEDITMTDFLEVNRQELRLWLREEPGA
FDWSVYSQHVCLIEGKGESWQEKECQLRARVKRILPIDVHRPQPLGAGGLAPLPADALVS
AFCLEAVSPDLASFQRALDHITTLLRPGGHLLLIGALEESWYLAGEARLAVVPVREEEVR
EALVRTATRCGICARTPMPAHLQTGVDDVKGIFFTRAQKKVGV
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|
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| BDBM50081952 |
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| n/a |
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| Name | BDBM50081952 |
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| Synonyms: | ((R)-7-Bromo-1,2,3,4-tetrahydro-isoquinolin-3-yl)-methanol | (7-Bromo-1,2,3,4-tetrahydro-isoquinolin-3-yl)-methanol | CHEMBL337144 |
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| Type | Small organic molecule |
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| Emp. Form. | C10H12BrNO |
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| Mol. Mass. | 242.112 |
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| SMILES | OC[C@H]1Cc2ccc(Br)cc2CN1 |
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| Structure | 
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