| Reaction Details |
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 | Report a problem with these data |
| Target | Growth hormone secretagogue receptor type 1 |
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| Ligand | BDBM50102238 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_84953 (CHEMBL697754) |
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| EC50 | 72±n/a nM |
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| Citation |  Palucki, BL; Feighner, SD; Pong, S; McKee, KK; Hreniuk, DL; Tan, C; Howard, AD; Van der Ploeg, LH; Patchett, AA; Nargund, RP Spiro(indoline-3,4'-piperidine) growth hormone secretagogues as ghrelin mimetics. Bioorg Med Chem Lett11:1955-7 (2001) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Growth hormone secretagogue receptor type 1 |
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| Name: | Growth hormone secretagogue receptor type 1 |
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| Synonyms: | GH-releasing peptide receptor | GHRP | GHS-R | GHSR | GHSR_HUMAN | Ghrelin Receptor (Growth Hormone Secretagogue Receptor Type 1) | Ghrelin receptor | Ghrelin receptor 1a (GHS-R1a) |
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| Type: | Receptor |
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| Mol. Mass.: | 41334.57 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Receptor binding studies use plasma membranes from LLC PK-1 cells transiently transfected with hGHSR1a. |
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| Residue: | 366 |
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| Sequence: | MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAG
NLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQ
FVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFV
LVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLW
RRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQI
SQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWT
ESSINT
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| BDBM50102238 |
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| n/a |
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| Name | BDBM50102238 |
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| Synonyms: | 2-[1-[1-aminomethylcarboxamido-2-heptylcarbonyloxy-(1S)-ethylcarboxamido]-2-hydroxy-(1S)-ethylcarboxamido]-3-phenyl-(2S)-propanoic acid | CHEMBL61663 |
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| Type | Small organic molecule |
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| Emp. Form. | C25H38N4O8 |
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| Mol. Mass. | 522.5912 |
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| SMILES | CCCCCCCC(=O)OC[C@H](NC(=O)CN)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccccc1)C(O)=O |
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| Structure | 
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