| Reaction Details |
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 | Report a problem with these data |
| Target | alpha-1,2-Mannosidase |
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| Ligand | BDBM50104298 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_32362 (CHEMBL643847) |
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| Ki | 98000±n/a nM |
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| Citation |  Popowycz, F; Gerber-Lemaire, S; Demange, R; Rodriguez-García, E; Asenjo, AT; Robina, I; Vogel, P Derivatives of (2R,3R,4S)-2-aminomethylpyrrolidine-3,4-diol are selective alpha-mannosidase inhibitors. Bioorg Med Chem Lett11:2489-93 (2001) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| alpha-1,2-Mannosidase |
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| Name: | alpha-1,2-Mannosidase |
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| Synonyms: | Alpha-mannosidase |
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| Type: | PROTEIN |
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| Mol. Mass.: | 65344.50 |
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| Organism: | Glycine max |
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| Description: | ChEMBL_32380 |
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| Residue: | 578 |
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| Sequence: | MARGSRSVGSSSSKWRYCNPSYYLKRPKRLALLFIVFVCVSFVFWDRQTLVREHQVEISE
LQKEVTDLKNLVDDLNNKQGGTSGKTDLGRKATKSSKDVLDDPIDIERREKVKEAMLHAW
GSYEKYAWGQDELQPQSKNGVNSFGGLGATLIDSLDTLYIMGLNEQFQKAREWVANSLDF
NKDYEASVFETTIRVVGGLLSAYDLSGDKVFLDKAIEIADRLLPAWNTPTGIPYNIINLS
HGRAHNPSWTGGESILADSGTEQLEFIVLSQRTGDLKYQQKVENVIAQLNKTFPDDGLLP
IYINPHSGAAGYSPITFGAMGDSFYEYLLKVWIQGNKTSSIKHYRDMWEKSMKGLSSLIR
RSTPSSFTYICEKNGGSLTDKMDELACFAPGMIALGSFGYSAADDSQKFLSLAEELAWTC
YNFYQSTPTKLAGENYFFHSGQDMSVGTSWNILRPETVESLFYLWRLTGNKTYQEWGWNI
FQAFEKNSRIESGYVGLKDVNSGVKDNMMQSFFLAETLKYFYLLFSPSSVISLDEWVFNT
EAHPLRIVTRHEEGLVKNLNEKQKPFSRIGGRKEGRSG
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| BDBM50104298 |
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| n/a |
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| Name | BDBM50104298 |
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| Synonyms: | 2-{[(Thiophen-2-ylmethyl)-amino]-methyl}-pyrrolidine-3,4-diol | CHEMBL84941 |
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| Type | Small organic molecule |
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| Emp. Form. | C10H16N2O2S |
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| Mol. Mass. | 228.311 |
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| SMILES | OC1CNC(CNCc2cccs2)C1O |
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| Structure | 
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