| Reaction Details |
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 | Report a problem with these data |
| Target | Beta-glucosidase A |
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| Ligand | BDBM50104301 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_37440 |
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| IC50 | 180000±n/a nM |
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| Citation |  Popowycz, F; Gerber-Lemaire, S; Demange, R; Rodriguez-García, E; Asenjo, AT; Robina, I; Vogel, P Derivatives of (2R,3R,4S)-2-aminomethylpyrrolidine-3,4-diol are selective alpha-mannosidase inhibitors. Bioorg Med Chem Lett11:2489-93 (2001) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Beta-glucosidase A |
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| Name: | Beta-glucosidase A |
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| Synonyms: | BGLS_CALSA | bglA |
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| Type: | PROTEIN |
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| Mol. Mass.: | 53484.21 |
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| Organism: | Caldocellum saccharolyticum |
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| Description: | ChEMBL_37437 |
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| Residue: | 455 |
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| Sequence: | MDMSFPKGFLWGAATASYQIEGAWNEDGKGESIWDRFTHQKRNILYGHNGDVACDHYHRF
EEDVSLMKELGLKAYRFSIAWTRIFPDGFGTVNQKGLEFYDRLINKLVENGIEPVVTLYH
WDLPQKLQDIGGWANPEIVNYYFDYAMLVINRYKDKVKKWITFNEPYCIAFLGYFHGIHA
PGIKDFKVAMDVVHSLMLSHFKVVKAVKENNIDVEVGITLNLTPVYLQTERLGYKVSEIE
REMVSLSSQLDNQLFLDPVLKGSYPQKLLDYLVQKDLLDSQKALSMQQEVKENFIFPDFL
GINYYTRAVRLYDENSSWIFPIRWEHPAGEYTEMGWEVFPQGLFDLLIWIKESYPQIPIY
ITENGAAYNDIVTEDGKVHDSKRIEYLKQHFEAARKAIENGVDLRGYFVWSLMDNFEWAM
GYTKRFGIIYVDYETQKRIKKDSFYFYQQYIKENS
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|
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| BDBM50104301 |
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| n/a |
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| Name | BDBM50104301 |
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| Synonyms: | 2-[((R)-1-Hydroxy-ethylamino)-methyl]-pyrrolidine-3,4-diol | BDBM50402987 | CHEMBL2206827 |
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| Type | Small organic molecule |
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| Emp. Form. | C7H16N2O3 |
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| Mol. Mass. | 176.2135 |
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| SMILES | C[C@H](O)NC[C@H]1NC[C@H](O)[C@@H]1O |r| |
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| Structure | 
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