| Reaction Details |
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 | Report a problem with these data |
| Target | Tissue alpha-L-fucosidase |
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| Ligand | BDBM50104396 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_34090 (CHEMBL647982) |
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| Ki | 4800±n/a nM |
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| Citation |  Robina, I; Moreno-Vargas, AJ; Fernández-Bolaños, JG; Fuentes, J; Demange, R; Vogel, P New leads for selective inhibitors of alpha-L-fucosidases. Synthesis and glycosidase inhibitory activities of [(2R,3S,4R)-3,4-dihydroxypyrrolidin-2-yl]furan derivatives. Bioorg Med Chem Lett11:2555-9 (2001) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Tissue alpha-L-fucosidase |
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| Name: | Tissue alpha-L-fucosidase |
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| Synonyms: | Alpha-L-fucosidase I | Alpha-L-fucoside fucohydrolase | FUCA1 | FUCO_HUMAN | Tissue alpha-L-fucosidase |
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| Type: | PROTEIN |
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| Mol. Mass.: | 53690.69 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_34088 |
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| Residue: | 466 |
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| Sequence: | MRAPGMRSRPAGPALLLLLLFLGAAESVRRAQPPRRYTPDWPSLDSRPLPAWFDEAKFGV
FIHWGVFSVPAWGSEWFWWHWQGEGRPQYQRFMRDNYPPGFSYADFGPQFTARFFHPEEW
ADLFQAAGAKYVVLTTKHHEGFTNWPSPVSWNWNSKDVGPHRDLVGELGTALRKRNIRYG
LYHSLLEWFHPLYLLDKKNGFKTQHFVSAKTMPELYDLVNSYKPDLIWSDGEWECPDTYW
NSTNFLSWLYNDSPVKDEVVVNDRWGQNCSCHHGGYYNCEDKFKPQSLPDHKWEMCTSID
KFSWGYRRDMALSDVTEESEIISELVQTVSLGGNYLLNIGPTKDGLIVPIFQERLLAVGK
WLSINGEAIYASKPWRVQWEKNTTSVWYTSKGSAVYAIFLHWPENGVLNLESPITTSTTK
ITMLGIQGDLKWSTDPDKGLFISLPQLPPSAVPAEFAWTIKLTGVK
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| BDBM50104396 |
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| n/a |
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| Name | BDBM50104396 |
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| Synonyms: | 5-(3,4-Dihydroxy-pyrrolidin-2-yl)-2-methyl-furan-3-carboxylic acid ethylamide | CHEMBL87234 |
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| Type | Small organic molecule |
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| Emp. Form. | C12H18N2O4 |
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| Mol. Mass. | 254.2823 |
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| SMILES | CCNC(=O)c1cc(oc1C)C1NCC(O)C1O |
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| Structure | 
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